The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
about
Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosisWD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activationBcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosisCompartmentalized expression of c-FLIP in lung tissues of patients with idiopathic pulmonary fibrosisGenetic models of abnormal apoptosis in lymphocytes.Apotosis of mature B cells.A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytesSystemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome proteinImmature and neurally differentiated mouse embryonic stem cells do not express a functional Fas/Fas ligand system.Molecular underpinning of B-cell anergy.Apoptosis and autoimmune thyroid disease: following a TRAIL to thyroid destruction?The NZM2410-derived lupus susceptibility locus Sle2c1 increases Th17 polarization and induces nephritis in fas-deficient miceCanine distemper virus infection leads to an inhibitory phenotype of monocyte-derived dendritic cells in vitro with reduced expression of co-stimulatory molecules and increased interleukin-10 transcription.Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells.Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicityCyclin-dependent kinase inhibitor Cdkn2c deficiency promotes B1a cell expansion and autoimmunity in a mouse model of lupus.Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide.Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I.Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression.Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy.Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenesAlterations of Fas and Fas-related molecules in patients with silicosis.Immunoregulatory CD4(-)CD8(-) T cells as a potential therapeutic tool for transplantation, autoimmunity, and cancer.Cytokine-mediated induction of human immunodeficiency virus (HIV) expression and cell death in chronically infected U1 cells: do tumor necrosis factor alpha and gamma interferon selectively kill HIV-infected cells?Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice.Accelerated atherosclerosis in ApoE deficient lupus mouse models.TNF-alpha sensitizes normal and fibrotic human lung fibroblasts to Fas-induced apoptosis.A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosisContribution of B-1a cells to systemic lupus erythematosus in the NZM2410 mouse modelCD95 is required for the early control of parasite burden in the liver of Leishmania donovani-infected mice.Fas apoptosis inhibitory molecules: more than death-receptor antagonists in the nervous system.Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.Fas-mediated cytotoxicity--a new immunoregulatory and pathogenic function of Th1 CD4+ T cells.FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor.The genetic basis of autoimmune disease in MRL-lpr/lpr mice.Apoptosis and its role in human disease.Gld and lpr mice: single gene mutant models for failed self tolerance.Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity.Fas, ceramide and serum withdrawal induce apoptosis via a common pathway in a type II Jurkat cell line.Cell death and longevity: implications of Fas-mediated apoptosis in T-cell senescence.
P2860
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P2860
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
description
1992 nî lūn-bûn
@nan
1992 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
name
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
@ast
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
@en
type
label
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
@ast
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
@en
prefLabel
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
@ast
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
@en
P1433
P1476
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
@en
P2093
Eisenberg RA
P304
P356
10.1016/0167-5699(92)90066-G
P577
1992-11-01T00:00:00Z