Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse
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Dietary manipulation and social isolation alter disease progression in a murine model of coronary heart diseaseIn Vitro and in Vivo Analysis of the Binding of the C Terminus of the HDL Receptor Scavenger Receptor Class B, Type I (SR-BI), to the PDZ1 Domain of Its Adaptor Protein PDZK1Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolismExposure to moderate arsenic concentrations increases atherosclerosis in ApoE-/- mouse modelExtrahepatic high-density lipoprotein receptor SR-BI and apoA-I protect against deep vein thrombosis in mice.Loss of PDZK1 causes coronary artery occlusion and myocardial infarction in Paigen diet-fed apolipoprotein E deficient mice.Thrombocytopenia and platelet abnormalities in high-density lipoprotein receptor-deficient mice.Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease.Scavenger receptor BI and high-density lipoprotein regulate thymocyte apoptosis in sepsisRole of the adaptor protein PDZK1 in controlling the HDL receptor SR-BISusceptibility gene for stroke or cerebral infarction in the Han population in Hunan Province of China.Excess cholesterol induces mouse egg activation and may cause female infertility.Normal hepatic cell surface localization of the high density lipoprotein receptor, scavenger receptor class B, type I, depends on all four PDZ domains of PDZK1.Negatively cooperative binding of high-density lipoprotein to the HDL receptor SR-BICholesteryl ester transfer protein expression partially attenuates the adverse effects of SR-BI receptor deficiency on cholesterol metabolism and atherosclerosis.SR-BI in bone marrow derived cells protects mice from diet induced coronary artery atherosclerosis and myocardial infarction.Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport.Scavenger receptor BI modulates platelet reactivity and thrombosis in dyslipidemia.Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport.Thematic review series: the immune system and atherogenesis. Recent insights into the biology of macrophage scavenger receptors.SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearanceInhibition of intestinal absorption of cholesterol by ezetimibe or bile acids by SC-435 alters lipoprotein metabolism and extends the lifespan of SR-BI/apoE double knockout mice.Oral absorption enhancement of probucol by PEGylated G5 PAMAM dendrimer modified nanoliposomesInfluence of PDZK1 on lipoprotein metabolism and atherosclerosis.HDL signaling and protection against coronary artery atherosclerosis in mice.Overexpression of the PDZ1 domain of PDZK1 blocks the activity of hepatic scavenger receptor, class B, type I by altering its abundance and cellular localization.ApoE knockout and knockin mice: the history of their contribution to the understanding of atherogenesisProgression and disruption of advanced atherosclerotic plaques in murine models.Anti-atherosclerotic and anti-diabetic properties of probucol and related compounds.Probucol inhibits LPS-induced microglia activation and ameliorates brain ischemic injury in normal and hyperlipidemic mice."Who's on first": determining the roster for the key players in the reverse cholesterol transport pathway.Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease.Pharmacological inhibition of ABCA1 degradation increases HDL biogenesis and exhibits antiatherogenesis.High-density lipoprotein metabolism and the human embryo.Scavenger Receptor Class B Type 1 Deletion Led to Coronary Atherosclerosis and Ischemic Heart Disease in Low-density Lipoprotein Receptor Knockout Mice on Modified Western-type Diet.Therapeutic strategies to deplete macrophages in atherosclerotic plaques.SR-BI: A Multifunctional Receptor in Cholesterol Homeostasis and Atherosclerosis.5th Annual International Conference on HDL Cholesterol: metabolic pathways and drug developments.Probucol protects against hypochlorite-induced endothelial dysfunction: identification of a novel pathway of probucol oxidation to a biologically active intermediate.Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering.
P2860
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P2860
Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Probucol prevents early corona ...... rotein E double knockout mouse
@ast
Probucol prevents early corona ...... rotein E double knockout mouse
@en
type
label
Probucol prevents early corona ...... rotein E double knockout mouse
@ast
Probucol prevents early corona ...... rotein E double knockout mouse
@en
prefLabel
Probucol prevents early corona ...... rotein E double knockout mouse
@ast
Probucol prevents early corona ...... rotein E double knockout mouse
@en
P2093
P2860
P50
P356
P1476
Probucol prevents early corona ...... rotein E double knockout mouse
@en
P2093
Anne Braun
Danita M Yoerger
Eliza Vasile
Helena E Miettinen
Joshua L Krieger
Mark J Post
Monty Krieger
Shamsah Ebrahim
Songwen Zhang
Teresa M Holm
P2860
P304
P356
10.1073/PNAS.1237725100
P407
P577
2003-05-27T00:00:00Z