Potent inhibitors of Plasmodium phospholipid metabolism with a broad spectrum of in vitro antimalarial activities.
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Inhibition of Plasmodium falciparum choline kinase by hexadecyltrimethylammonium bromide: a possible antimalarial mechanismCholine analogues in malaria chemotherapyA chemical proteomics approach for the search of pharmacological targets of the antimalarial clinical candidate albitiazolium in Plasmodium falciparum using photocrosslinking and click chemistryAn Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma bruceiLocalization of the phosphoethanolamine methyltransferase of the human malaria parasite Plasmodium falciparum to the Golgi apparatusA systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparumSymmetrical choline-derived dications display strong anti-kinetoplastid activity.Pharmacological properties of a new antimalarial bisthiazolium salt, T3, and a corresponding prodrug, TE3.Potent antihematozoan activity of novel bisthiazolium drug T16: evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.Design and Synthesis of Novel Hybrid Molecules against Malaria.Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytesLipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexansAntiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives.Prodrugs of bisthiazolium salts are orally potent antimalarialsNovel antimalarial drug targets: hope for new antimalarial drugs.A novel live-dead staining methodology to study malaria parasite viability.Synthesis and antiplasmodial activity of streptocyanine/peroxide and streptocyanine/4-aminoquinoline hybrid dyes.In vivo antimalarial activities of mono- and bis quaternary ammonium salts interfering with Plasmodium phospholipid metabolismSynthesis and antimalarial properties of streptocyanine dyes.High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death.Reliability of antimalarial sensitivity tests depends on drug mechanisms of action.Unraveling the mode of action of the antimalarial choline analog G25 in Plasmodium falciparum and Saccharomyces cerevisiae.New insight into the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium, a new type of antimalarial.Characterization of the lipid-binding domain of the Plasmodium falciparum CTP:phosphocholine cytidylyltransferase through synthetic-peptide studies.Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidateDevelopment of the first oral bioprecursors of bis-alkylguanidine antimalarial drugs.Evaluation of bis-alkylamidoxime O-alkylsulfonates as orally available antimalarials.Effect of a bis-thiazolium compound on the biosynthesis of Plasmodium falciparum phospholipids.Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite
P2860
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P2860
Potent inhibitors of Plasmodium phospholipid metabolism with a broad spectrum of in vitro antimalarial activities.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Potent inhibitors of Plasmodiu ...... vitro antimalarial activities.
@ast
Potent inhibitors of Plasmodiu ...... vitro antimalarial activities.
@en
type
label
Potent inhibitors of Plasmodiu ...... vitro antimalarial activities.
@ast
Potent inhibitors of Plasmodiu ...... vitro antimalarial activities.
@en
prefLabel
Potent inhibitors of Plasmodiu ...... vitro antimalarial activities.
@ast
Potent inhibitors of Plasmodiu ...... vitro antimalarial activities.
@en
P2093
P2860
P1476
Potent inhibitors of Plasmodiu ...... vitro antimalarial activities.
@en
P2093
Henri J Vial
Marie L Ancelin
Michèle Calas
Pascal Ringwald
Serge Herbuté
Valérie Vidal-Sailhan
P2860
P304
P356
10.1128/AAC.47.8.2590-2597.2003
P407
P577
2003-08-01T00:00:00Z