Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis - Wikidata - awgldk - TriplyDB

Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

http://www.wikidata.org/entity/Q35166545

about

Opposite Interplay between PPAR Gamma and Canonical Wnt/Beta-Catenin Pathway in Amyotrophic Lateral Sclerosis Mechanisms of Muscle Denervation in Aging: Insights from a Mouse Model of Amyotrophic Lateral Sclerosis Resveratrol: A Focus on Several Neurodegenerative Diseases New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond Free radicals: properties, sources, targets, and their implication in various diseases Mitochondrial dysfunction in amyotrophic lateral sclerosis - a valid pharmacological target?Histone deacetylases and their role in motor neuron degeneration Skeletal Muscle Satellite Cells, Mitochondria, and MicroRNAs: Their Involvement in the Pathogenesis of ALS Mitochondrial dysfunction in neurodegenerative diseases PGC-1α negatively regulates extrasynaptic NMDAR activity and excitotoxicity PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis.Mitochondrial Effects of PGC-1alpha Silencing in MPP+ Treated Human SH-SY5Y Neuroblastoma Cells.Resveratrol ameliorates motor neuron degeneration and improves survival in SOD1(G93A) mouse model of amyotrophic lateral sclerosis A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset.Decreased level of olfactory receptors in blood cells following traumatic brain injury and potential association with tauopathy Sirtuins as therapeutic targets of ALS.Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf.Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway.Potential roles of PINK1 for increased PGC-1α-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes.PPAR agonists as therapeutics for CNS trauma and neurological diseases A plural role for lipids in motor neuron diseases: energy, signaling and structure.Turn up the power - pharmacological activation of mitochondrial biogenesis in mouse models.Carbamylated-oxidized LDL: proatherosclerotic effects on endothelial cells and macrophages PGC-1α: a master gene that is hard to master.Peroxisome proliferator-activated receptor-γ cofactors in neurodegeneration.AMPK Signalling and Defective Energy Metabolism in Amyotrophic Lateral Sclerosis.Does PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders?How does resveratrol influence the genesis of some neurodegenerative diseases?Additive Neuroprotective Effects of the Multifunctional Iron Chelator M30 with Enriched Diet in a Mouse Model of Amyotrophic Lateral Sclerosis.Could Sirtuin Activities Modify ALS Onset and Progression?Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency.Statins accelerate disease progression and shorten survival in SOD1(G93A) mice.Mitochondrial quality control in amyotrophic lateral sclerosis: towards a common pathway?RETRACTED: Bezafibrate improves mitochondrial function in the CNS of a mouse model of mitochondrial encephalopathy.Caloric Restriction and the Nutrient-Sensing PGC-1α in Mitochondrial Homeostasis: New Perspectives in Neurodegeneration.

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P2860

Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

http://www.wikidata.org/entity/Q35166545

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Peroxisome proliferator activa ...... amyotrophic lateral sclerosis

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Peroxisome proliferator activa ...... amyotrophic lateral sclerosis

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type

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Peroxisome proliferator activa ...... amyotrophic lateral sclerosis

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Peroxisome proliferator activa ...... amyotrophic lateral sclerosis

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Peroxisome proliferator activa ...... amyotrophic lateral sclerosis

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Peroxisome proliferator activa ...... amyotrophic lateral sclerosis

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Molecular Neurodegeneration

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Peroxisome proliferator activa ...... amyotrophic lateral sclerosis

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Alice Cheng

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Fei Chen

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Merina Varghese

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Paul Marano

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Prashant Vempati

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Sadiq Hassan

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Shrishailam Yemul

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Wei Zhao

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Xianjuan Qian

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Yong Pan

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P2860

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease

PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

Metabolic control through the PGC-1 family of transcription coactivators

Unraveling the mechanisms involved in motor neuron degeneration in ALS

Mitochondria in sporadic amyotrophic lateral sclerosis.

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction.

A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration.

Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2

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51

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10.1186/1750-1326-6-51

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1

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6

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Giulio Maria Pasinetti

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51504220

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1023913486

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21771318

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amyotrophic lateral sclerosis

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3156746

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