Toll-like receptor 4 promotes α-synuclein clearance and survival of nigral dopaminergic neurons.
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The Role of Toll-Like Receptor 4 in Infectious and Noninfectious InflammationReview: Multiple system atrophy: emerging targets for interventional therapiesGlia and alpha-synuclein in neurodegeneration: A complex interactionThe complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's diseaseThe role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?Animal models of multiple system atrophyInflammation and α-synuclein's prion-like behavior in Parkinson's disease--is there a link?Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunityMicroglia development and functionSeeking a mechanism for the toxicity of oligomeric α-synucleinPhagocytosis of microglia in the central nervous system diseasesNew insights on NOX enzymes in the central nervous system.Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity.Towards translational therapies for multiple system atrophyToll-like receptor 4 stimulation with monophosphoryl lipid A ameliorates motor deficits and nigral neurodegeneration triggered by extraneuronal α-synucleinopathyNeuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microgliaSex Differences in monocytes and TLR4 associated immune responses; implications for systemic lupus erythematosus (SLE)A spirulina-enhanced diet provides neuroprotection in an α-synuclein model of Parkinson's disease.Exploring Braak's Hypothesis of Parkinson's Disease.Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson's disease.Toll-like receptor expression in the blood and brain of patients and a mouse model of Parkinson's diseaseImmune aging, dysmetabolism, and inflammation in neurological diseases.Aspects of innate immunity and Parkinson's disease.The Interplay between Alpha-Synuclein Clearance and SpreadingNeuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies.Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinical ImplicationsEicosanoid receptor subtype-mediated opposing regulation of TLR-stimulated expression of astrocyte glial-derived neurotrophic factor.When human immunodeficiency virus meets chemokines and microglia: neuroprotection or neurodegeneration?Leucine-rich repeat kinase 2 (LRRK2) regulates α-synuclein clearance in microglia.Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases.Models of multiple system atrophyBladder dysfunction in a transgenic mouse model of multiple system atrophy.Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease.Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model.Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.Vitamin D and Parkinson's disease.The role of glia in α-synucleinopathies.Oxidative and nitrative alpha-synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies.The role of inflammation in sporadic and familial Parkinson's disease.Animal models of Parkinson's disease: a gateway to therapeutics?
P2860
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P2860
Toll-like receptor 4 promotes α-synuclein clearance and survival of nigral dopaminergic neurons.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Toll-like receptor 4 promotes ...... f nigral dopaminergic neurons.
@ast
Toll-like receptor 4 promotes ...... f nigral dopaminergic neurons.
@en
type
label
Toll-like receptor 4 promotes ...... f nigral dopaminergic neurons.
@ast
Toll-like receptor 4 promotes ...... f nigral dopaminergic neurons.
@en
prefLabel
Toll-like receptor 4 promotes ...... f nigral dopaminergic neurons.
@ast
Toll-like receptor 4 promotes ...... f nigral dopaminergic neurons.
@en
P2093
P2860
P50
P921
P1476
Toll-like receptor 4 promotes ...... f nigral dopaminergic neurons.
@en
P2093
Lisa Fellner
Markus Reindl
Nadia Stefanova
P2860
P304
P356
10.1016/J.AJPATH.2011.04.013
P407
P577
2011-06-14T00:00:00Z