A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line. - Wikidata - awgldk - TriplyDB

A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line.

A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line.

http://www.wikidata.org/entity/Q35171318

about

Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase Proteasome inhibition by fellutamide B induces nerve growth factor synthesis Omuralide and vibralactone: differences in the proteasome- β-lactone-γ-lactam binding scaffold alter target preferences Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin The ubiquitin-proteasome pathway and proteasome inhibitors Proteasome inhibitors block development of Plasmodium spp.How an inhibitor of the HIV-I protease modulates proteasome activity.Calcium-activated proteases are critical for refilling depleted vesicle stores in cultured sensory-motor synapses of Aplysia.The ubiquitin-proteasome pathway and synaptic plasticity.Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice.Local ubiquitin-proteasome-mediated proteolysis and long-term synaptic plasticity.The enteropathogenic Escherichia coli effector Cif induces delayed apoptosis in epithelial cells.Lactacystin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers.Stereospecific total syntheses of proteasome inhibitors omuralide and lactacystin Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression.Natural compounds with proteasome inhibitory activity for cancer prevention and treatment.Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter The ubiquitin-proteasome system in HIV replication: potential targets for antiretroviral therapy.The ubiquitin-proteasome pathway in cancer Proteasome activity is required for the stage-specific transformation of a protozoan parasite.Consequences of impaired purine recycling in dopaminergic neurons.Novel aspects of degradation of T cell receptor subunits from the endoplasmic reticulum (ER) in T cells: importance of oligosaccharide processing, ubiquitination, and proteasome-dependent removal from ER membranes.From bortezomib to other inhibitors of the proteasome and beyond.Proteasome inhibition triggers activity-dependent increase in the size of the recycling vesicle pool in cultured hippocampal neurons.A short and efficient synthesis of (-)-7-methylomuralide, a potent proteasome inhibitor Proteasome regulators: activators and inhibitors.Mechanisms for PDGF, a serum cytokine, stimulating loss of corneal keratocyte crystallins.Neurotrophic natural products: chemistry and biology.Remodeling natural products: chemistry and serine hydrolase activity of a rocaglate-derived β-lactone.Synthesis and pharmacology of proteasome inhibitors.Ionizing radiation induces neuronal differentiation of Neuro-2a cells via PI3-kinase and p53-dependent pathways.Proteolysis, synaptic plasticity and memory.N-terminal deletion does not affect α-synuclein membrane binding, self-association and toxicity in human neuroblastoma cells, unlike yeast.Lactacystin requires reactive oxygen species and Bax redistribution to induce mitochondria-mediated cell death.Differential effects of all-trans retinoic acid on the growth of human keratinocytes and mouth carcinoma epidermoid cultures. Involvement of GRIM-19 and complex I of the respiratory chain.Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins.Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells.Alzheimer's disease: correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome.Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation.Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin.

P2860

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P2860

A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line.

http://www.wikidata.org/entity/Q35171318

description

1994 nî lūn-bûn

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1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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1994 թվականի ապրիլին հրատարակված գիտական հոդված

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1994年の論文

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1994年学术文章

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1994年学术文章

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1994年学术文章

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1994年学术文章

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1994年学术文章

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1994年學術文章

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name

A beta-lactone related to lact ...... in an osteosarcoma cell line.

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A beta-lactone related to lact ...... in an osteosarcoma cell line.

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type

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A beta-lactone related to lact ...... in an osteosarcoma cell line.

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A beta-lactone related to lact ...... in an osteosarcoma cell line.

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prefLabel

A beta-lactone related to lact ...... in an osteosarcoma cell line.

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A beta-lactone related to lact ...... in an osteosarcoma cell line.

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Proceedings of the National Academy of Sciences of the United States of America

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A beta-lactone related to lact ...... in an osteosarcoma cell line.

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Corey EJ

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Fenteany G

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Reichard GA

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Schreiber SL

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Standaert RF

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P2860

A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins

Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity

Inhibition of 3-hydroxy-3-methylglutaryl-CoA synthase and cholesterol biosynthesis by beta-lactone inhibitors and binding of these inhibitors to the enzyme

Thrombin modulates and reverses neuroblastoma neurite outgrowth

Inhibition of protein kinase C induces differentiation in Neuro-2a cells.

The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation.

Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth.

Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses.

Multiple neurite formation in neuroblastoma cell lines by griseolic acid, a potent inhibitor of cyclic nucleotide phosphodiesterases.

Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A synthase by antibiotic 1233A and other beta-lactones.

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3358-3362

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10.1073/PNAS.91.8.3358

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8

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91

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15039009

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8159752

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