Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons
about
Transcription start site associated RNAs (TSSaRNAs) are ubiquitous in all domains of lifeDrosophila Muller F Elements Maintain a Distinct Set of Genomic Properties Over 40 Million Years of EvolutionTranscription Blockage Leads to New BeginningsGetting up to speed with transcription elongation by RNA polymerase IIP-TEFb, the super elongation complex and mediator regulate a subset of non-paused genes during early Drosophila embryo developmentA single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting.Chromatin, DNA structure and alternative splicingTranscription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation.The Integrator complex controls the termination of transcription at diverse classes of gene targets.Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cellsRNA Pol II transcription model and interpretation of GRO-seq data.Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.Genome-wide binding of MBD2 reveals strong preference for highly methylated lociBase-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq).Multiplexed gene control reveals rapid mRNA turnover.Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate.Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolideChromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle.Widespread rearrangement of 3D chromatin organization underlies polycomb-mediated stress-induced silencing.Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks.RNA polymerase II pausing can be retained or acquired during activation of genes involved in the epithelial to mesenchymal transition.GAGA factor maintains nucleosome-free regions and has a role in RNA polymerase II recruitment to promotersVisualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo.Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other StressesGenome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution.Native elongating transcript sequencing reveals human transcriptional activity at nucleotide resolution.Genome-wide profiling of RNA polymerase transcription at nucleotide resolution in human cells with native elongating transcript sequencing.P-TEFb Kinase Activity Is Essential for Global Transcription, Resumption of Meiosis and Embryonic Genome Activation in Pig.Structure of silent transcription intervals and noise characteristics of mammalian genesGdown1 Associates Efficiently with RNA Polymerase II after Promoter Clearance and Displaces TFIIF during Transcript ElongationTranscriptome-Wide Discovery of PASRs (Promoter-Associated Small RNAs) and TASRs (Terminus-Associated Small RNAs) in Arabidopsis thaliana.Genomic landscape of CpG rich elements in humanExpanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus.Introns and gene expression: cellular constraints, transcriptional regulation, and evolutionary consequences.Defective histone supply causes changes in RNA polymerase II elongation rate and cotranscriptional pre-mRNA splicingQuantitative regulation of FLC via coordinated transcriptional initiation and elongationRNA polymerase II pausing as a context-dependent reader of the genome.Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells.Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes.Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9
P2860
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P2860
Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
name
Genome-wide dynamics of Pol II ...... pausing, chromatin, and exons
@ast
Genome-wide dynamics of Pol II ...... pausing, chromatin, and exons
@en
type
label
Genome-wide dynamics of Pol II ...... pausing, chromatin, and exons
@ast
Genome-wide dynamics of Pol II ...... pausing, chromatin, and exons
@en
prefLabel
Genome-wide dynamics of Pol II ...... pausing, chromatin, and exons
@ast
Genome-wide dynamics of Pol II ...... pausing, chromatin, and exons
@en
P2093
P2860
P356
P1433
P1476
Genome-wide dynamics of Pol II ...... pausing, chromatin, and exons
@en
P2093
Hojoong Kwak
Iris Jonkers
John T Lis
P2860
P304
P356
10.7554/ELIFE.02407
P407
P577
2014-04-29T00:00:00Z