Recent developments in the discovery of FFA1 receptor agonists as novel oral treatment for type 2 diabetes mellitus.
about
Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40.Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational AnalysisCharacterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4.Treatment of type 2 diabetes by free Fatty Acid receptor agonists.Design, Synthesis, and Structure-Activity Relationships of Bavachinin Analogues as Peroxisome Proliferator-Activated Receptor γ Agonists.Investigational insulin secretagogues for type 2 diabetes.The Role and Future of FFA1 as a Therapeutic Target.Free fatty acid receptor agonists for the treatment of type 2 diabetes: drugs in preclinical to phase II clinical development.Fasiglifam (TAK-875): Mechanistic Investigation and Retrospective Identification of Hazards for Drug Induced Liver Injury.Polymorphic Variation in FFA Receptors: Functions and Consequences.Key Questions for Translation of FFA Receptors: From Pharmacology to Medicines.Free Fatty Acid Receptor 1 (FFAR1) as an Emerging Therapeutic Target for Type 2 Diabetes Mellitus: Recent Progress and Prevailing Challenges.Identification of an Orally Efficacious GPR40/FFAR1 Receptor Agonist.Structural basis for the agonist action at free fatty acid receptor 1 (FFA1R or GPR40).Quercetin/oleic acid-based G-protein-coupled receptor 40 ligands as new insulin secretion modulators.Pharmacological Tool Compounds for the Free Fatty Acid Receptor 4 (FFA4/GPR120).Novel FFA1 (GPR40) agonists containing spirocyclic periphery: polar azine periphery as a driver of potency.Ligands at Free Fatty Acid Receptor 1 (GPR40).Synthesis of GPR40 targeting 3 H- and 18 F-probes towards selective beta cell imaging.Structural basis for GPR40 allosteric agonism and incretin stimulation.
P2860
Q35117995-D93BB4B5-8870-4D27-B2AB-C056862BBCE6Q36006492-1B3EEFE8-AFC4-4298-8713-E93703683A99Q38240702-741196B2-747C-4594-80DC-02A1973C9A5FQ38249182-13DD81CB-EFC9-43C7-8D24-39B5322BDCC9Q38727792-0F84B06A-6DB7-4B87-ADEF-396E4C5BFE9AQ38735419-149FB597-AEFF-4C8F-99EF-D7D192CF7C1EQ38799812-A8ABCDD9-9FEF-4C93-8C9A-1431935A0CCEQ38832716-923A46C8-AF71-4CAB-9C71-348542D90624Q38958120-464FF35D-DF99-498B-9A6F-28F97393D096Q39013784-5B164751-8817-4824-AC70-E2F8273DCDC6Q39016250-35A974B4-F154-45E0-950D-7F7A12CE445DQ39192856-E6069417-93D7-492F-A407-A55082E900CCQ45599801-F72D3B3D-1308-4CF1-AC65-B0A9564D3029Q47606086-72CEC3D7-2B90-4A80-9866-D15A0CABE97BQ47611209-87A0DEE1-A51E-49CC-96DA-E7E331A6DD19Q51347974-46DDF1C2-422B-42A0-9F67-0E1BFAED28BBQ51363044-F403B391-E7D6-4F31-AA52-2014EB56BDCAQ51377008-F2DAD4D0-89A8-4514-BEDC-C438E9888CA4Q51711049-846DDCA6-2BB5-4195-9C91-620ECF23222EQ52309488-71BD8478-4256-4000-B8DC-FCEC56FE555C
P2860
Recent developments in the discovery of FFA1 receptor agonists as novel oral treatment for type 2 diabetes mellitus.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Recent developments in the dis ...... for type 2 diabetes mellitus.
@ast
Recent developments in the dis ...... for type 2 diabetes mellitus.
@en
type
label
Recent developments in the dis ...... for type 2 diabetes mellitus.
@ast
Recent developments in the dis ...... for type 2 diabetes mellitus.
@en
prefLabel
Recent developments in the dis ...... for type 2 diabetes mellitus.
@ast
Recent developments in the dis ...... for type 2 diabetes mellitus.
@en
P1476
Recent developments in the dis ...... for type 2 diabetes mellitus.
@en
P2093
Elisabeth Defossa
Michael Wagner
P304
P356
10.1016/J.BMCL.2014.05.019
P407
P577
2014-05-16T00:00:00Z