Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage - Wikidata - awgldk - TriplyDB

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

http://www.wikidata.org/entity/Q35180889

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Functions of PARylation in DNA Damage Repair Pathways Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress Real Estate in the DNA Damage Response: Ubiquitin and SUMO Ligases Home in on DNA Double-Strand Breaks Readers of poly(ADP-ribose): designed to be fit for purpose RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination Base Excision Repair, a Pathway Regulated by Posttranslational Modifications ADP-ribosyltransferases and poly ADP-ribosylation Molecular Insights into Poly(ADP-ribose) Recognition and Processing.Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke.Elovanoids are novel cell-specific lipid mediators necessary for neuroprotective signaling for photoreceptor cell integrity New facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.Modulation of poly(ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.The guanine-quadruplex structure in the human c-myc gene's promoter is converted into B-DNA form by the human poly(ADP-ribose)polymerase-1.Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair.A quantitative assay reveals ligand specificity of the DNA scaffold repair protein XRCC1 and efficient disassembly of complexes of XRCC1 and the poly(ADP-ribose) polymerase 1 by poly(ADP-ribose) glycohydrolase.Analysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-Ring finger protein 146/Iduna is a poly(ADP-ribose) polymer binding and PARsylation dependent E3 ubiquitin ligase.Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs.Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53.PHRF1 promotes genome integrity by modulating non-homologous end-joining.Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitylation after degradation of poly(ADP-ribose).PARP1 regulates the protein stability and proapoptotic function of HIPK2.Overexpression of RNF146 in non-small cell lung cancer enhances proliferation and invasion of tumors through the Wnt/β-catenin signaling pathway TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-β-Catenin Pathway in Glutamate Excitotoxicity Injury.On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1.New synaptic and molecular targets for neuroprotection in Parkinson's disease.Reprogramming cellular events by poly(ADP-ribose)-binding proteins Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling.The recognition and removal of cellular poly(ADP-ribose) signals.Poly(ADP-ribosyl)ation in regulation of chromatin structure and the DNA damage response.ADP-ribosylation: activation, recognition, and removal Regulation of Wnt/β-catenin signaling by posttranslational modifications

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Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

http://www.wikidata.org/entity/Q35180889

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

@ast

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

@en

type

label

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

@ast

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

@en

prefLabel

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

@ast

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

@en

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PNAS.1108799108

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Proceedings of the National Academy of Sciences of the United States of America

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Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

@en

P2093

Byoung Dae Lee

http://www.w3.org/2001/XMLSchema#string

Guy G Poirier

http://www.w3.org/2001/XMLSchema#string

Han Seok Ko

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Ho Chul Kang

http://www.w3.org/2001/XMLSchema#string

Jean-Philippe Gagné

http://www.w3.org/2001/XMLSchema#string

Joo-Ho Shin

http://www.w3.org/2001/XMLSchema#string

Shaida A Andrabi

http://www.w3.org/2001/XMLSchema#string

Valina L Dawson

http://www.w3.org/2001/XMLSchema#string

Yun-Il Lee

http://www.w3.org/2001/XMLSchema#string

Yunjong Lee

http://www.w3.org/2001/XMLSchema#string

P2860

RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

A phosphorylation-driven ubiquitination switch for cell-cycle control

Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)

Poly(ADP-ribose): novel functions for an old molecule

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

The ubiquitin-proteasome pathway: on protein death and cell life

PARP inhibition: PARP1 and beyond

The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation.

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14103-14108

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scholarly article

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10.1073/PNAS.1108799108

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34

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108

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2011-08-08T00:00:00Z

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51555554

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21825151

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3161609

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