The ARL2 GTPase is required for mitochondrial morphology, motility, and maintenance of ATP levels.

The ARL2 GTPase is required for mitochondrial morphology, motility, and maintenance of ATP levels.

Item
http://www.wikidata.org/entity/Q35183960
Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamicsThe abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors.Higher order signaling: ARL2 as regulator of both mitochondrial fusion and microtubule dynamics allows integration of 2 essential cell functions.Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).Effect of the N-Terminal Helix and Nucleotide Loading on the Membrane and Effector Binding of Arl2/3.Plasmids for variable expression of proteins targeted to the mitochondrial matrix or intermembrane spaceSorting of lipidated cargo by the Arl2/Arl3 systemNucleotide Binding to ARL2 in the TBCD∙ARL2∙β-Tubulin Complex Drives Conformational Changes in β-Tubulin.The ARL2 GTPase regulates mitochondrial fusion from the intermembrane space.GTPase-activating protein Elmod2 is essential for meiotic progression in mouse oocytes.ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membraneThe Arf activator GBF1 localizes to plasma membrane sites involved in cell adhesion and motility.Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef.ARL2 overexpression inhibits glioma proliferation and tumorigenicity via down-regulating AXL.Mild therapeutic hypothermia protects against cerebral ischemia/reperfusion injury by inhibiting miR-15b expression in rats
P2860

The ARL2 GTPase is required for mitochondrial morphology, motility, and maintenance of ATP levels.

Item
http://www.wikidata.org/entity/Q35183960
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2014 nî lūn-bûn
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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2014 թվականի հունիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
The ARL2 GTPase is required fo ...... and maintenance of ATP levels.
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The ARL2 GTPase is required fo ...... and maintenance of ATP levels.
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The ARL2 GTPase is required fo ...... and maintenance of ATP levels.
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The ARL2 GTPase is required fo ...... and maintenance of ATP levels.
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The ARL2 GTPase is required fo ...... and maintenance of ATP levels.
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The ARL2 GTPase is required fo ...... and maintenance of ATP levels.
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P1433
P1476
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P356
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The ARL2 GTPase is required fo ...... and maintenance of ATP levels.
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P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0099270
P407
P433
P478
P50
P577
P5875
P698
P932