K-ras is an essential gene in the mouse with partial functional overlap with N-ras. - Wikidata - awgldk - TriplyDB

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

http://www.wikidata.org/entity/Q35192456

about

M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6 Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and function Paired-like homeoprotein ESXR1 acts as a sequence-specific transcriptional repressor of the human K-ras gene The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.R-Ras3/M-Ras induces neuronal differentiation of PC12 cells through cell-type-specific activation of the mitogen-activated protein kinase cascade.A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas K-ras/PI3K-Akt signaling is essential for zebrafish hematopoiesis and angiogenesis A natural small molecule, catechol, induces c-Myc degradation by directly targeting ERK2 in lung cancer Ras-induced cellular events (review)Structure and function of the C-terminal hypervariable region of K-Ras4B in plasma membrane targetting and transformation Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis H-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cells Germline KRAS mutations cause Noonan syndrome Lung epithelial branching program antagonizes alveolar differentiation Genetic interaction between Rb and K-ras in the control of differentiation and tumor suppression Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis.Suprachiasmatic nucleus circadian oscillatory protein, a novel binding partner of K-Ras in the membrane rafts, negatively regulates MAPK pathway Rhes is involved in striatal function Involvement of a small GTP-binding protein (G protein) regulator, small G protein GDP dissociation stimulator, in antiapoptotic cell survival signaling Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.Lipophilic bisphosphonates plus rapamycin: a deadly combination for KRAS-mutated lung adenocarcinoma Characteristics of lung cancers harboring NRAS mutations Ras oncogenes: split personalities MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathway Ras history: The saga continues.Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells.Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine.Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis.Analysis of k-ras nuclear expression in fibroblasts and mesangial cells Activated Ras alters lens and corneal development through induction of distinct downstream targets.Ras membrane orientation and nanodomain localization generate isoform diversity

P2860

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P2860

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

http://www.wikidata.org/entity/Q35192456

description

1997 nî lūn-bûn

@nan

1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1997年の論文

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1997年論文

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1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

name

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

@ast

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

@en

type

label

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

@ast

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

@en

prefLabel

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

@ast

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

@en

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Genes & Development

P1476

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

@en

P2093

D Greenbaum

http://www.w3.org/2001/XMLSchema#string

E Murphy

http://www.w3.org/2001/XMLSchema#string

E Schmitt

http://www.w3.org/2001/XMLSchema#string

H Umanoff

http://www.w3.org/2001/XMLSchema#string

K Cichowski

http://www.w3.org/2001/XMLSchema#string

K Mercer

http://www.w3.org/2001/XMLSchema#string

L Johnson

http://www.w3.org/2001/XMLSchema#string

R Kucherlapati

http://www.w3.org/2001/XMLSchema#string

R T Bronson

http://www.w3.org/2001/XMLSchema#string

T Jacks

http://www.w3.org/2001/XMLSchema#string

P2860

Genetic analysis of yeast RAS1 and RAS2 genes.

All ras proteins are polyisoprenylated but only some are palmitoylated

The GTPase superfamily: a conserved switch for diverse cell functions

The ins and outs of Raf kinases

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

Small GTP-binding proteins and the regulation of the actin cytoskeleton

MAPKs: new JNK expands the group

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

ras oncogenes in human cancer: a review

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2468-2481

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10.1101/GAD.11.19.2468

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19

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P478

11

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P577

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9334313

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316567

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