Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains
about
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tauNuMA: an unusually long coiled-coil related protein in the mammalian nucleusMicrotubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262Characterization of pinin, a novel protein associated with the desmosome-intermediate filament complexTau protein binds to microtubules through a flexible array of distributed weak sitesRegulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegenerationHyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filamentsThe simian virus 40 small-t intron, present in many common expression vectors, leads to aberrant splicingA nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) proteinMAP2 and tau bind longitudinally along the outer ridges of microtubule protofilamentsPathophysiological Function of ADAMTS Enzymes on Molecular Mechanism of Alzheimer's DiseaseTau: The Center of a Signaling Nexus in Alzheimer's DiseaseThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetTau and tauopathiesProbing protein interactions in living mammalian cells on a microtubule benchDirect force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules.Targeting mRNA for Alzheimer's and related dementias.Argyrophilic grain diseasePhosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamicsA novel tau-tubulin kinase from bovine brainMicrotubule bundling by tau proteins in vivo: analysis of functional domainsMicrotubule-dependent oligomerization of tau. Implications for physiological tau function and tauopathiesAssociation of tyrosine phosphatase epsilon with microtubules inhibits phosphatase activity and is regulated by the epidermal growth factor receptor.The CDC20 gene product of Saccharomyces cerevisiae, a beta-transducin homolog, is required for a subset of microtubule-dependent cellular processes.FTDP-17 mutations in Tau alter the regulation of microtubule dynamics: an "alternative core" model for normal and pathological Tau action.Modulation of microtubule dynamics by tau in living cells: implications for development and neurodegenerationPrimary structure of high molecular weight tau present in the peripheral nervous systemBinding of copper (II) ion to an Alzheimer's tau peptide as revealed by MALDI-TOF MS, CD, and NMR.Three repeat isoforms of tau inhibit assembly of four repeat tau filamentsFunctional implications for the microtubule-associated protein tau: localization in oligodendrocytes.Mechanisms of tau-induced neurodegeneration.Identification of nuclear tau isoforms in human neuroblastoma cellsThe switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding regionPhosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegenerationThe number of repeat sequences in microtubule-associated protein 4 affects the microtubule surface properties.Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease.Microtubule stabilization by assembly-promoting microtubule-associated proteins: a repeat performance.Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons.Sequence of a human MAP-2 region sharing epitopes with Alzheimer neurofibrillary tangles.The cytoskeleton in neurodegenerative diseases.
P2860
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P2860
Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains
description
1989 nî lūn-bûn
@nan
1989 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Tau consists of a set of prote ...... nd variable N-terminal domains
@ast
Tau consists of a set of prote ...... nd variable N-terminal domains
@en
type
label
Tau consists of a set of prote ...... nd variable N-terminal domains
@ast
Tau consists of a set of prote ...... nd variable N-terminal domains
@en
prefLabel
Tau consists of a set of prote ...... nd variable N-terminal domains
@ast
Tau consists of a set of prote ...... nd variable N-terminal domains
@en
P2093
P2860
P356
P1476
Tau consists of a set of prote ...... nd variable N-terminal domains
@en
P2093
Drechsel D
Kirschner MW
Martin DW Jr
P2860
P304
P356
10.1128/MCB.9.4.1381
P407
P577
1989-04-01T00:00:00Z