Enzymatic transition state poise and transition state analogues.
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Transition state analogue discrimination by related purine nucleoside phosphorylasesAlkaline phosphatase mono- and diesterase reactions: comparative transition state analysisInhibition and Structure of Trichomonas vaginalis Purine Nucleoside Phosphorylase with Picomolar Transition State Analogues †Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase †Structure of Mandelate Racemase with Bound Intermediate Analogues Benzohydroxamate and CupferronEnzymatic transition states, transition-state analogs, dynamics, thermodynamics, and lifetimesCombined QM/MM and path integral simulations of kinetic isotope effects in the proton transfer reaction between nitroethane and acetate ion in water.Determinants of catalytic power and ligand binding in glutamate racemase.Catalytic reaction mechanism of acetylcholinesterase determined by Born-Oppenheimer ab initio QM/MM molecular dynamics simulations.LacZ β-galactosidase: structure and function of an enzyme of historical and molecular biological importance.Purine and pyrimidine pathways as targets in Plasmodium falciparum.Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimicsStructure and inhibition of a quorum sensing target from Streptococcus pneumoniaeTransition-state variation in human, bovine, and Plasmodium falciparum adenosine deaminases.Computation of kinetic isotope effects for enzymatic reactions.Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases.Mechanisms for enzymatic cleavage of the N-glycosidic bond in DNA.Inhibition of LuxS by S-ribosylhomocysteine analogues containing a [4-aza]ribose ring.Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases.Transition states of uncatalyzed hydrolysis and aminolysis reactions of a ribosomal P-site substrate determined by kinetic isotope effects.Pyrophosphate interactions at the transition states of Plasmodium falciparum and human orotate phosphoribosyltransferasesTransition state analysis of thymidine hydrolysis by human thymidine phosphorylase.Pinpointing dynamic coupling in enzymes for efficient drug design.Transition state analysis of the arsenolytic depyrimidination of thymidine by human thymidine phosphorylase.Soybean epoxide hydrolase: identification of the catalytic residues and probing of the reaction mechanism with secondary kinetic isotope effects.Interpreting medium ring canonical conformers by a triangular plane tessellation of the macrocycle.Activation of the hetero-octameric ATP phosphoribosyl transferase through subunit interface rearrangement by a tRNA synthetase paralog.Kinetic Isotope Effects and Transition State Structure for Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase from Plasmodium falciparum.Enzymatic Kinetic Isotope Effects from Path-Integral Free Energy Perturbation Theory.Discovery of new β-D-galactosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening.Discovery of new β-D-glucosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening.
P2860
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P2860
Enzymatic transition state poise and transition state analogues.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Enzymatic transition state poise and transition state analogues.
@ast
Enzymatic transition state poise and transition state analogues.
@en
type
label
Enzymatic transition state poise and transition state analogues.
@ast
Enzymatic transition state poise and transition state analogues.
@en
prefLabel
Enzymatic transition state poise and transition state analogues.
@ast
Enzymatic transition state poise and transition state analogues.
@en
P356
P1476
Enzymatic transition state poise and transition state analogues.
@en
P2093
Vern L Schramm
P304
P356
10.1021/AR0200495
P577
2003-08-01T00:00:00Z