Purine and pyrimidine pathways as targets in Plasmodium falciparum.
about
Advances in kinetic isotope effect measurement techniques for enzyme mechanism studyTransition-state inhibitors of purine salvage and other prospective enzyme targets in malariaHost reticulocytes provide metabolic reservoirs that can be exploited by malaria parasitesLys48 ubiquitination during the intraerythrocytic cycle of the rodent malaria parasite, Plasmodium chabaudiComprehensive quantitative analysis of purines and pyrimidines in the human malaria parasite using ion-pairing ultra-performance liquid chromatography-mass spectrometry.Purine import into malaria parasites as a target for antimalarial drug development.Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasitesDecreased erythrocyte nucleoside transport and hENT1 transporter expression in glucose 6-phosphate dehydrogenase deficiency.Bioenergetics-based modeling of Plasmodium falciparum metabolism reveals its essential genes, nutritional requirements, and thermodynamic bottlenecks.Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug developmentArtemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7.Antimalarial and antimicrobial activities of 8-Aminoquinoline-Uracils metal complexes.Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic developmentDistinct Prominent Roles for Enzymes of Plasmodium berghei Heme Biosynthesis in Sporozoite and Liver Stage Maturation.Inhibition of nucleotide biosynthesis potentiates the antifungal activity of amphotericin B.Medicinal chemistry of fluorinated cyclic and acyclic nucleoside phosphonates.From crystal to compound: structure-based antimalarial drug discovery.Solution structures of purine base analogues 6-chloroguanine, 8-azaguanine and allopurinol.Modeling metabolism and stage-specific growth of Plasmodium falciparum HB3 during the intraerythrocytic developmental cycle.Metabolic modeling helps interpret transcriptomic changes during malaria.Cloning, expression and purification of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum.Role of W181 in modulating kinetic properties of Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase.Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase from Trypanosoma brucei.
P2860
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P2860
Purine and pyrimidine pathways as targets in Plasmodium falciparum.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Purine and pyrimidine pathways as targets in Plasmodium falciparum.
@ast
Purine and pyrimidine pathways as targets in Plasmodium falciparum.
@en
type
label
Purine and pyrimidine pathways as targets in Plasmodium falciparum.
@ast
Purine and pyrimidine pathways as targets in Plasmodium falciparum.
@en
prefLabel
Purine and pyrimidine pathways as targets in Plasmodium falciparum.
@ast
Purine and pyrimidine pathways as targets in Plasmodium falciparum.
@en
P2093
P2860
P1476
Purine and pyrimidine pathways as targets in Plasmodium falciparum.
@en
P2093
Keith Z Hazleton
María Belén Cassera
Vern L Schramm
Yong Zhang
P2860
P304
P356
10.2174/156802611796575948
P577
2011-01-01T00:00:00Z