The Ataxin-2 protein is required for microRNA function and synapse-specific long-term olfactory habituation. - Wikidata - awgldk - TriplyDB

The Ataxin-2 protein is required for microRNA function and synapse-specific long-term olfactory habituation.

The Ataxin-2 protein is required for microRNA function and synapse-specific long-term olfactory habituation.

http://www.wikidata.org/entity/Q35202757

about

Altered ribostasis: RNA-protein granules in degenerative disorders Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease Cell biology of spinocerebellar ataxia Current understanding of the role of microRNAs in spinocerebellar ataxias ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics Non-coding RNA in neural function, disease, and aging 12q24 locus association with type 1 diabetes: SH2B3 or ATXN2?Spinocerebellar Ataxia Type 2 Is Associated with the Extracellular Loss of Superoxide Dismutase but Not Catalase Activity.3'UTRs take a long shot in the brain.Ataxin-2: From RNA Control to Human Health and Disease The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease.The emerging roles of microRNAs in the pathogenesis of frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS) spectrum disorders ETS1 regulates the expression of ATXN2.A genetic screen for olfactory habituation mutations in Drosophila: analysis of novel foraging alleles and an underlying neural circuit.Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.Olfactory habituation: fresh insights from flies.A novel paradigm for nonassociative long-term memory in Drosophila: predator-induced changes in oviposition behavior.Modification of Male Courtship Motivation by Olfactory Habituation via the GABAA Receptor in Drosophila melanogaster.P-body assembly requires DDX6 repression complexes rather than decay or Ataxin2/2L complexes.Cause or Effect: Misregulation of microRNA Pathways in Neurodegeneration.Modifiers of solid RNP granules control normal RNP dynamics and mRNA activity in early development Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models.Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2 Drosophila ORB protein in two mushroom body output neurons is necessary for long-term memory formation.Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways Drosophila ataxin-2 gene encodes two differentially expressed isoforms and its function in larval fat body is crucial for development of peripheral tissues MiR-980 Is a Memory Suppressor MicroRNA that Regulates the Autism-Susceptibility Gene A2bp1.Dysregulation of mRNA Localization and Translation in Genetic Disease FMRP and Ataxin-2 function together in long-term olfactory habituation and neuronal translational control.Relationships between Stress Granules, Oxidative Stress, and Neurodegenerative Diseases.MicroRNAs shape the neuronal landscape.MicroRNAs and neurodegeneration: role and impact.Protein aggregation in amyotrophic lateral sclerosis.Synaptic control of local translation: the plot thickens with new characters.Small non-coding RNAs add complexity to the RNA pathogenic mechanisms in trinucleotide repeat expansion diseases.MicroRNAs in neuronal communication.Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate.MicroRNA function in Drosophila memory formation.Hypo- and Hyper-Assembly Diseases of RNA-Protein Complexes.

P2860

513d773311034577b1e63b8b269f6652bbe40cf4 9010dc13408be5f5e3e2f538b75262213542bac1

P248

Q24604643-2168DF21-213F-4844-9C97-7E633F52777A Q26764958-F323548F-3429-49D0-A881-382A10332480 Q26829511-0FDD77F4-2027-4C1C-BE95-53AFC7CB8FF6 Q27028008-F100E016-AE87-4EEC-BB6D-38C081F386B8 Q27307794-6053C09A-50C7-4A10-8614-950FF4527E7F Q28080682-628A5A65-7CDC-4E0B-9194-C0F36DA090CE Q28242134-287CEC3A-D6EB-4885-9F47-FD7055C306A0 Q33790012-B3D335FE-281F-44C3-8E13-6786DE4BFBFC Q33793219-25C57AA2-CCD6-42A0-A0A3-EC9F31DF50AC Q33836795-445BA037-4B7D-4118-B212-8CF1C7E19AE8 Q34278940-92F8AB67-895E-4C42-92D3-F2D79682C1ED Q34289150-D81DBDC0-F50F-4B0B-9480-2736CC6C34BB Q34353055-DCCDF323-9A76-45F4-9E7E-20B286197BDA Q34390181-78524DF0-4DE7-46B8-A2AB-CC3FE872BEC0 Q34532151-AF26F45D-972E-47E2-9D5E-0DC692AEFC1C Q35196519-5A4408D6-DB74-437E-896F-0CB17819CD67 Q35202644-192FEACB-E32E-4097-BE32-1528C46F2764 Q35342550-BB039C56-61F4-4C5C-B330-CFD69BAA659D Q35739666-7A779182-9C99-4C2E-8467-12BB6C07E235 Q35849087-946DE8E4-F89F-4084-B27D-F7F73BA581A3 Q35875886-E1C818F2-8D61-49A7-8945-25E74F86E1C5 Q36266144-875027DF-DAEA-4FEE-85C1-CC1E80B2B777 Q36355055-70108416-E39C-4782-8EDF-101B11D90256 Q36477656-A9A48EE9-426A-4256-ACB2-B404F2623E53 Q36835612-4A06A462-96C4-4A80-9B06-965CD2925A4D Q37099358-0B0BB6A9-D81A-4326-AA3D-86B7312C4064 Q37393103-BEAAD245-0C97-43DD-AB3E-609579DE1F3F Q37405733-363E088B-BE3D-4635-9CD0-08B59FBFF945 Q37444939-DA0B7E25-B0F1-4245-A97F-7775E7645766 Q37475190-632E7954-9EC3-4411-8582-DC909C89CD01 Q37618198-F127CA4C-26FC-4D07-8DC6-5366C50936BD Q38033846-463B0E13-37EF-4984-81A6-61B7A8B92BB8 Q38048423-BF03CBAB-9902-4A4B-9C22-0D558B1D39FA Q38106862-0E2CC11E-DF9A-4A29-84ED-D47A007543F3 Q38161293-2CE8AF0A-0A8D-4EBC-B258-08EB9A3EA81B Q38172118-DE4CA581-D2FD-41AA-A4CE-CB90621AE5EE Q38175350-86CE9ABA-9BC3-405C-85F0-7871F615D486 Q38300785-224034CA-6D72-4312-9CD8-089AE008E785 Q38434926-C6A6D093-798D-4C9F-8137-9495EC0397D5 Q38855284-84C6AB53-19A1-40B2-B377-210161BB15DE

P2860

The Ataxin-2 protein is required for microRNA function and synapse-specific long-term olfactory habituation.

http://www.wikidata.org/entity/Q35202757

description

2011 nî lūn-bûn

@nan

2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年学术文章

@wuu

2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

name

The Ataxin-2 protein is requir ...... ng-term olfactory habituation.

@ast

The Ataxin-2 protein is requir ...... ng-term olfactory habituation.

@en

type

label

The Ataxin-2 protein is requir ...... ng-term olfactory habituation.

@ast

The Ataxin-2 protein is requir ...... ng-term olfactory habituation.

@en

prefLabel

The Ataxin-2 protein is requir ...... ng-term olfactory habituation.

@ast

The Ataxin-2 protein is requir ...... ng-term olfactory habituation.

@en

P1433

Q35202757-8DE920E9-C6BA-4174-BBF1-875A81F06A50

P1476

Q35202757-F15044FD-3B9D-44C3-8755-EC49F13EA25D

P2093

Q35202757-1CCBE634-D1F7-4D38-8E19-52D35204B8EA

Q35202757-39D1DE40-1DBF-4A0F-8215-DCDB09A4D47C

Q35202757-5C8B68D8-9824-4474-80AE-A94AB3838847

Q35202757-5EF76522-4D3B-4E49-8F86-FFFE7C45DA37

Q35202757-60697B90-1EDA-4781-88F3-DDA95C743B8B

Q35202757-67B64C35-CDE8-4BE3-829D-07627C8976B0

Q35202757-82FFB7B2-ADE6-468D-8386-4595CCBEA371

P2860

Q35202757-065A24DF-8660-4415-9B2C-BF32CAD8D1F8

Q35202757-085BF72E-7A37-4361-B42E-5DF252B87F2A

Q35202757-0EF50BDD-2D7D-433E-9528-42D0C20BCDEA

Q35202757-13D6D81F-3FA3-4324-8A8E-2C3882F409D8

Q35202757-14B72191-B0D5-47DF-A0D8-CFA29D5E99DC

Q35202757-15509F4D-46FD-4EA8-8F2C-687826D0B246

Q35202757-15975537-806F-4B8B-A6E8-D97B2EC21C98

Q35202757-1D415755-3A9A-4CA5-87F3-7978347DA9FE

Q35202757-1DC6EDFB-5440-4013-BC6C-3A549925D5CA

Q35202757-255A17F2-4568-479C-8A75-66CA32409C0F

P304

Q35202757-3B725C63-E48F-4D3C-9713-36BB93A3B766

P31

Q35202757-F425D737-98A2-4F90-B714-EEE88DDEDFD0

P356

Q35202757-85ED0525-17A3-4C5B-9AE2-3D82779CF4A0

P407

Q35202757-67C8AB0B-59E6-4642-B3C4-D5C00C7EB2ED

P433

Q35202757-2437DFA9-EA26-454B-88E6-0B0EA6BBD720

P478

Q35202757-4A3BB482-91E9-4DBF-857C-697CE14C00EA

P50

Q35202757-B26D5C8A-24F1-4205-B8E0-7F11AD5ADA5C

Q35202757-C1BA6924-37FD-4DFC-80F5-7190F1763C05

P577

Q35202757-BA39982E-7216-4746-806E-5FEDA94BE138

P5875

Q35202757-87BDE1BC-DDAB-4A91-BE9A-5372981A6472

P698

Q35202757-42B74001-88A1-44B5-87BD-B37E8BFDA2B7

P921

Q35202757-175E703B-8F01-4A4E-A4EC-B5CA6DB56E91

P932

Q35202757-0F8E4559-2690-4FF7-9378-005668401DAA

P356

PNAS.1107198108

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

The Ataxin-2 protein is requir ...... ong-term olfactory habituation

@en

P2093

Adrian Dervan

http://www.w3.org/2001/XMLSchema#string

Aoife Larkin

http://www.w3.org/2001/XMLSchema#string

Cathal McCann

http://www.w3.org/2001/XMLSchema#string

Eimear E Holohan

http://www.w3.org/2001/XMLSchema#string

Roy Parker

http://www.w3.org/2001/XMLSchema#string

Sudeshna Das

http://www.w3.org/2001/XMLSchema#string

Veronica Rodrigues

http://www.w3.org/2001/XMLSchema#string

P2860

Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

Identification of Drosophila MicroRNA targets

Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation

An integrative approach to gain insights into the cellular function of human ataxin-2

A Drosophila homolog of the polyglutamine disease gene SCA2 is a dosage-sensitive regulator of actin filament formation

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

P304

E655-62

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1107198108

http://www.w3.org/2001/XMLSchema#string

P407

P433

36

http://www.w3.org/2001/XMLSchema#string

P478

108

http://www.w3.org/2001/XMLSchema#string

P50

P577

2011-07-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51527167

http://www.w3.org/2001/XMLSchema#string

P698

21795609

http://www.w3.org/2001/XMLSchema#string

P921

P932

3169144

http://www.w3.org/2001/XMLSchema#string