Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans - Wikidata - awgldk - TriplyDB

Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans

Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans

http://www.wikidata.org/entity/Q35202803

about

Unified theory of Alzheimer's disease (UTAD): implications for prevention and curative therapy Extracellular vesicles round off communication in the nervous system Drug repositioning approaches for the discovery of new therapeutics for Alzheimer's disease Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases Neuronal clearance of amyloid-β by endocytic receptor LRP1.Investigational drugs for treating agitation in persons with dementia.Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease Fluoxetine attenuates the impairment of spatial learning ability and prevents neuron loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer's disease mice.A tricyclic antidepressant, amoxapine, reduces amyloid-β generation through multiple serotonin receptor 6-mediated targets.Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease.Depressive Symptoms in Clinical and Incipient Alzheimer's Disease.Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.Role of citalopram in the treatment of agitation in Alzheimer's disease.An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice.A depressive endophenotype of mild cognitive impairment and Alzheimer's disease Specific serotonergic denervation affects tau pathology and cognition without altering senile plaques deposition in APP/PS1 mice.Characterization of a brain permeant fluorescent molecule and visualization of Aβ parenchymal plaques, using real-time multiphoton imaging in transgenic mice Potential natural products for Alzheimer's disease: targeted search using the internal ribosome entry site of tau and amyloid-β precursor protein.Amyloid deposition in Parkinson's disease and cognitive impairment: a systematic review.Sleep disturbances in Alzheimer's and Parkinson's diseases.Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis.Alzheimer's disease and gut microbiota.Serotonin 6 receptor controls Alzheimer's disease and depression Cerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers.Amyloid Hypothesis: Is There a Role for Antiamyloid Treatment in Late-Life Depression?ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.Rapid in vivo measurement of β-amyloid reveals biphasic clearance kinetics in an Alzheimer's mouse model.Cerebral amyloid deposition and serotoninergic innervation in Parkinson disease.Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo.Escitalopram attenuates β-amyloid-induced tau hyperphosphorylation in primary hippocampal neurons through the 5-HT1A receptor mediated Akt/GSK-3β pathway The serotonergic system and cognitive function Fluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1.Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer's Disease.Behavioural Phenotyping of APPswe/PS1δE9 Mice: Age-Rrelated Changes and Effect of Long-Term Paroxetine Treatment.Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease.Epigenetic dysregulation of brainstem nuclei in the pathogenesis of Alzheimer's disease: looking in the correct place at the right time?Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease.A review: treatment of Alzheimer's disease discovered in repurposed agents.

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Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans

http://www.wikidata.org/entity/Q35202803

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

name

Serotonin signaling is associa ...... in transgenic mice and humans

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Serotonin signaling is associa ...... in transgenic mice and humans

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type

label

Serotonin signaling is associa ...... in transgenic mice and humans

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Serotonin signaling is associa ...... in transgenic mice and humans

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prefLabel

Serotonin signaling is associa ...... in transgenic mice and humans

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Serotonin signaling is associa ...... in transgenic mice and humans

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PNAS.1107411108

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Proceedings of the National Academy of Sciences of the United States of America

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Serotonin signaling is associa ...... in transgenic mice and humans

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P2093

Anshul Sathyan

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Brianne M Disabato

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Davinder Hayreh

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Deborah K Verges

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Gina D'Angelo

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Hyejin Yoon

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Jessica L Restivo

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Jungsu Kim

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Tammie Benzinger

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P2860

Untreated Depression and Hippocampal Volume Loss

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

APP processing and synaptic function

The Clinical Dementia Rating (CDR): current version and scoring rules

Alzheimer's disease

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14968-14973

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scholarly article

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Yvette I Sheline

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2011-08-22T00:00:00Z

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51601261

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21873225

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