Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.
about
Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesEnd invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes.Efficient bacterial transcription of DNA nanocircle vectors with optimized single-stranded promoters.Strand invasion by mixed base PNAs and a PNA-peptide chimeraPeptide nucleic acid (PNA) binding-mediated gene regulation.Peptide nucleic acids: versatile tools for gene therapy strategies.Triplex-forming molecules: from concepts to applications.Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA.Isolation of active genes containing CAG repeats by DNA strand invasion by a peptide nucleic acid.Transcription-mediated binding of peptide nucleic acid (PNA) to double-stranded DNA: sequence-specific suicide transcriptionKinetic sequence discrimination of cationic bis-PNAs upon targeting of double-stranded DNA.DNA compaction induced by a cationic polymer or surfactant impact gene expression and DNA degradationSynthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubilityRecent advances in the development of peptide nucleic acid as a gene-targeted drug.Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells.A Bis(guanidinium)alcohol Attached to a Hairpin Polyamide: Synthesis, DNA Binding, and Plasmid Cleavage.Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression.Periodic-shRNA molecules are capable of gene silencing, cytotoxicity and innate immune activation in cancer cellsTriplex-forming peptide nucleic acids induce heritable elevations in gamma-globin expression in hematopoietic progenitor cells.Peptide nucleic acid (PNA) binding and its effect on in vitro transcription in friedreich's ataxia triplet repeats.miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs.Peptide nucleic acids: a review on recent patents and technology transfer.Destabilization of tRNA3(Lys) from the primer-binding site of HIV-1 genome by anti-A loop polyamide nucleotide analogSite-directed gene mutation at mixed sequence targets by psoralen-conjugated pseudo-complementary peptide nucleic acidsThe 30-kDa protein binding to the "initiator" of the baculovirus polyhedrin promoter also binds specifically to the coding strand.Structural diversity of target-specific homopyrimidine peptide nucleic acid-dsDNA complexes.Regulation of transcription by synthetic DNA-bending agents.Sequence-unrestricted, Watson-Crick recognition of double helical B-DNA by (R)-miniPEG-γPNAs.Extended target sequence specificity of PNA-minor-groove binder conjugates.Specific gene blockade shows that peptide nucleic acids readily enter neuronal cells in vivo.Stability and transformations of bis-PNA/DNA triplex structural isomers.Inhibition of transcription by bisPNA-peptide conjugates.Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence.Synthesis and properties of DNA-PNA chimeric oligomers.Kinetic analysis of specificity of duplex DNA targeting by homopyrimidine peptide nucleic acids.Influence of DNA template choice on transcription and inhibition of Escherichia coli RNA polymerase.Rolling-Circle RNA Synthesis: Circular Oligonucleotides as Efficient Substrates for T7 RNA Polymerase.A novel mode for transcription inhibition mediated by PNA-induced R-loops with a model in vitro system.Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities.Synthesis of nucleobase-caged peptide nucleic acids having improved photochemical properties.
P2860
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P2860
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.
description
1994 nî lūn-bûn
@nan
1994 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.
@ast
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.
@en
type
label
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.
@ast
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.
@en
prefLabel
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.
@ast
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.
@en
P2093
P2860
P356
P1476
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.
@en
P2093
Buchardt O
Møllegaard NE
Nielsen PE
P2860
P304
P356
10.1073/PNAS.91.9.3892
P407
P577
1994-04-01T00:00:00Z