Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression.
about
Characteristics of compounds that cross the blood-brain barrierPeptide nucleic acid (PNA) binding-mediated gene regulation.Peptide nucleic acids: versatile tools for gene therapy strategies.Identification and analysis of the minimal promoter activity of a novel noncoding nuclear RNA gene, AncR-1, from the honeybee (Apis mellifera L.).Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids.Inhibition of human immunodeficiency virus replication by cell membrane-crossing oligomersAntisense imaging of gene expression in the brain in vivoInhibiting gene expression with peptide nucleic acid (PNA)--peptide conjugates that target chromosomal DNA.Altered morphine-induced analgesia in neurotensin type 1 receptor null mice.Quantification of tumor-derived cell free DNA(cfDNA) by digital PCR (DigPCR) in cerebrospinal fluid of patients with BRAFV600 mutated malignancies.Isolation of peptide transport system-6 from brain endothelial cells: therapeutic effects with antisense inhibition in Alzheimer and stroke models.Pharmacomodulation of microRNA Expression in Neurocognitive Diseases: Obstacles and Future Opportunities.Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon.PNA as a potential modulator of COL7A1 gene expression in dominant dystrophic epidermolysis bullosa: a physico-chemical study.Combination of a new generation of PNAs with a peptide-based carrier enables efficient targeting of cell cycle progression.PNAs breach the blood-brain barrier?Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities.Brain Delivery of Multifunctional Dendrimer Protein Bioconjugates.
P2860
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P2860
Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Peptide nucleic acids targeted ...... ically reduce gene expression.
@ast
Peptide nucleic acids targeted ...... ically reduce gene expression.
@en
type
label
Peptide nucleic acids targeted ...... ically reduce gene expression.
@ast
Peptide nucleic acids targeted ...... ically reduce gene expression.
@en
prefLabel
Peptide nucleic acids targeted ...... ically reduce gene expression.
@ast
Peptide nucleic acids targeted ...... ically reduce gene expression.
@en
P2093
P2860
P356
P1476
Peptide nucleic acids targeted ...... ically reduce gene expression.
@en
P2093
C L Douglas
D J McCormick
E Richelson
J A Stewart
P2860
P304
P356
10.1073/PNAS.96.12.7053
P407
P577
1999-06-01T00:00:00Z