PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis - Wikidata - awgldk - TriplyDB

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

http://www.wikidata.org/entity/Q35204528

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Fundamentals of cancer metabolism Cancer stem cell metabolism Integration of Mitochondrial Targeting for Molecular Cancer Therapeutics Treatment Strategies that Enhance the Efficacy and Selectivity of Mitochondria-Targeted Anticancer Agents PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion Distinctive properties of metastasis-initiating cells Metabolic reprogramming in cancer cells: glycolysis, glutaminolysis, and Bcl-2 proteins as novel therapeutic targets for cancer ROS homeostasis and metabolism: a critical liaison for cancer therapy Nrf2 protects mitochondrial decay by oxidative stress Grainyhead-like 2 Reverses the Metabolic Changes Induced by the Oncogenic Epithelial-Mesenchymal Transition: Effects on Anoikis Therapeutic inhibition of mitochondrial function induces cell death in starvation-resistant renal cell carcinomas A neuronal network of mitochondrial dynamics regulates metastasis.Migration and invasion of drug-resistant lung adenocarcinoma cells are dependent on mitochondrial activity Cryptolepine inhibits melanoma cell growth through coordinated changes in mitochondrial biogenesis, dynamics and metabolic tumor suppressor AMPKα1/2-LKB1.Metabolic characterization of invaded cells of the pancreatic cancer cell line, PANC-1.Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint.Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?Downregulation of ATG5-dependent macroautophagy by chaperone-mediated autophagy promotes breast cancer cell metastasis.Evolving Lessons on the Complex Role of AMPK in Normal Physiology and Cancer.MitoCeption as a new tool to assess the effects of mesenchymal stem/stromal cell mitochondria on cancer cell metabolism and function L-Lactate Protects Skin Fibroblasts against Aging-Associated Mitochondrial Dysfunction via Mitohormesis.Down-Regulation of NDUFB9 Promotes Breast Cancer Cell Proliferation, Metastasis by Mediating Mitochondrial Metabolism.Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells.Correlating two-photon excited fluorescence imaging of breast cancer cellular redox state with seahorse flux analysis of normalized cellular oxygen consumption.The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.MicroRNA-mRNA regulatory networking fine-tunes the porcine muscle fiber type, muscular mitochondrial respiratory and metabolic enzyme activities.Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance.Technical Insights into Highly Sensitive Isolation and Molecular Characterization of Fixed and Live Circulating Tumor Cells for Early Detection of Tumor Invasion.Oxidative stress inhibits distant metastasis by human melanoma cells.Muscle Transcriptional Profile Based on Muscle Fiber, Mitochondrial Respiratory Activity, and Metabolic Enzymes.Coupling the modules of EMT and stemness: A tunable 'stemness window' model The Emerging Hallmarks of Cancer Metabolism Molecular Pathways: Mitochondrial Reprogramming in Tumor Progression and Therapy.High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant.Suppression of mitochondrial respiration with auraptene inhibits the progression of renal cell carcinoma: involvement of HIF-1α degradation.5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits.Screening SIRT1 Activators from Medicinal Plants as Bioactive Compounds against Oxidative Damage in Mitochondrial Function.Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer.

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P2860

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

http://www.wikidata.org/entity/Q35204528

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

PGC-1α mediates mitochondrial ...... er cells to promote metastasis

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Nature Cell Biology

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PGC-1α mediates mitochondrial ...... er cells to promote metastasis

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P2093

Aline Damascena

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Fernanda Machado de Carvalho

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John M Asara

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Joyce T O'Connell

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Karina N Gonzalez Herrera

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Klaus Pantel

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Ludmilla Thome Domingos Chinen

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Marcia C Haigis

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Rafael M Rocha

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Raghu Kalluri

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P2860

Direct regulation of TWIST by HIF-1alpha promotes metastasis

Understanding the Warburg effect: the metabolic requirements of cell proliferation

The basics of epithelial-mesenchymal transition

PGC-1 family coactivators and cell fate: roles in cancer, neurodegeneration, cardiovascular disease and retrograde mitochondria-nucleus signalling

The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

Epithelial-mesenchymal transitions in tumour progression

On the Origin of Cancer Cells

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

P2888

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992-1003, 1-15

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10.1038/NCB3039

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10

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16

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25241037

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phosphorylation

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4369153

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