Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. - Wikidata - awgldk - TriplyDB

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

http://www.wikidata.org/entity/Q35212670

about

The RNA helicase A in malignant transformation Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic Landscapes Potential approaches to the treatment of Ewing's sarcoma Recent advances in targeted therapy for Ewing sarcoma Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9 Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model Discovery of Small Molecules that Inhibit the Disordered Protein, p27(Kip1).Enhanced construction of gene regulatory networks using hub gene information YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model.Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.Loss of Ewing sarcoma EWS allele promotes tumorigenesis by inducing chromosomal instability in zebrafish.Generation of conditional oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing and homology-directed repair.An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development A polypeptide from the junction region sequence of EWS-FLI1 inhibits Ewing's sarcoma cells, interacts with the EWS-FLI1 and partner proteins.HnRNP-L promotes prostate cancer progression by enhancing cell cycling and inhibiting apoptosis.An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer.Nucleoplasmic Nup98 controls gene expression by regulating a DExH/D-box protein.RNA Binding Protein as an Emerging Therapeutic Target for Cancer Prevention and Treatment.EWS-FLI1 and RNA helicase A interaction inhibitor YK-4-279 inhibits growth of neuroblastoma.Targeting RNA helicases in cancer: The translation trap.Fusions in solid tumours: diagnostic strategies, targeted therapy, and acquired resistance.Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.Gene expression changes associated with chemotherapy resistance in Ewing sarcoma cells.

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P2860

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

http://www.wikidata.org/entity/Q35212670

description

2015 nî lūn-bûn

@nan

2015 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի մարտին հրատարակված գիտական հոդված

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2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

@ast

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

@en

type

label

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

@ast

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

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prefLabel

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

@ast

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

@en

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PNAS.1500536112

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.

@en

P2093

Aleksandra Dakic

http://www.w3.org/2001/XMLSchema#string

Aykut Üren

http://www.w3.org/2001/XMLSchema#string

Cathy H Wu

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Elizabeth R Lawlor

http://www.w3.org/2001/XMLSchema#string

Hayriye V Erkizan

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Toretsky

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Mats E Ljungman

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Michelle T Paulsen

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Saravana P Selvanathan

http://www.w3.org/2001/XMLSchema#string

Songtao Yu

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P2860

p68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex.

A role for RNA helicase A in post-transcriptional regulation of HIV type 1

Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure

Transcriptional consequences of topoisomerase inhibition

Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review

Children's Oncology Group's 2013 blueprint for research: bone tumors

Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures

Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts

Human Ku70/80 associates physically with telomerase through interaction with hTERT

The splicing factor U1C represses EWS/FLI-mediated transactivation

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E1307-16

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scholarly article

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10.1073/PNAS.1500536112

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11

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112

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Garrett T Graham

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2015-03-03T00:00:00Z

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25737553

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4371969

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