Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease.
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Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's diseaseSequence determinants of protein aggregation: tools to increase protein solubility.Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophyHuntington's diseaseElongation kinetics of polyglutamine peptide fibrils: a quartz crystal microbalance with dissipation study.Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.To fold or not to fold: modulation and consequences of Hsp90 inhibition.The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative DiseasesProteostasis in striatal cells and selective neurodegeneration in Huntington's disease.Activation of salt shock response leads to solubilisation of mutant huntingtin in Saccharomyces cerevisiae.Polyglutamine shows a urea-like affinity for unfolded cytosolic protein.Glutamine: A novel approach to chemotherapy-induced toxicity.The Leber congenital amaurosis protein AIPL1 modulates the nuclear translocation of NUB1 and suppresses inclusion formation by NUB1 fragments.Molecular chaperone dysfunction in neurodegenerative diseases and effects of curcumin.Chaperones increase association of tau protein with microtubules.Protein aggregation as bacterial inclusion bodies is reversible.Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatographySpatial quality control bypasses cell-based limitations on proteostasis to promote prion curing.Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model.A yeast model for polyalanine-expansion aggregation and toxicitySigma-1 receptor chaperones and diseasesAggregation kinetics of interrupted polyglutamine peptidesHuntington's Disease and Striatal Signaling.Heat shock proteins as emerging therapeutic targets.NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy.Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease modelChaperones in autophagy.Heat shock proteins in the retina: Focus on HSP70 and alpha crystallins in ganglion cell survival.Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson diseaseHsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligaseApplying Hsp104 to protein-misfolding disorders.Molecular mechanisms and potential therapeutical targets in Huntington's disease.Huntington's disease, calcium, and mitochondria.Physical chemistry of polyglutamine: intriguing tales of a monotonous sequence.NMDA Receptor Activity in Neuropsychiatric Disorders.Association of heat-shock proteins in various neurodegenerative disorders: is it a master key to open the therapeutic door?Huntington's disease: from gene to potential therapy.Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104.Huntington's Disease: Mechanisms of Pathogenesis and Therapeutic Strategies.
P2860
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P2860
Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease.
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Bacterial and yeast chaperones ...... odels of Huntington's disease.
@ast
Bacterial and yeast chaperones ...... odels of Huntington's disease.
@en
type
label
Bacterial and yeast chaperones ...... odels of Huntington's disease.
@ast
Bacterial and yeast chaperones ...... odels of Huntington's disease.
@en
prefLabel
Bacterial and yeast chaperones ...... odels of Huntington's disease.
@ast
Bacterial and yeast chaperones ...... odels of Huntington's disease.
@en
P2093
P2860
P356
P1476
Bacterial and yeast chaperones ...... odels of Huntington's disease.
@en
P2093
Carmichael J
Chatellier J
Milstein C
Rubinsztein DC
Woolfson A
P2860
P304
P356
10.1073/PNAS.170280697
P407
P50
P577
2000-08-01T00:00:00Z