Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease. - Wikidata - awgldk - TriplyDB

Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease.

Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease.

http://www.wikidata.org/entity/Q35212735

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Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease Sequence determinants of protein aggregation: tools to increase protein solubility.Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy Huntington's disease Elongation kinetics of polyglutamine peptide fibrils: a quartz crystal microbalance with dissipation study.Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.To fold or not to fold: modulation and consequences of Hsp90 inhibition.The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases Proteostasis in striatal cells and selective neurodegeneration in Huntington's disease.Activation of salt shock response leads to solubilisation of mutant huntingtin in Saccharomyces cerevisiae.Polyglutamine shows a urea-like affinity for unfolded cytosolic protein.Glutamine: A novel approach to chemotherapy-induced toxicity.The Leber congenital amaurosis protein AIPL1 modulates the nuclear translocation of NUB1 and suppresses inclusion formation by NUB1 fragments.Molecular chaperone dysfunction in neurodegenerative diseases and effects of curcumin.Chaperones increase association of tau protein with microtubules.Protein aggregation as bacterial inclusion bodies is reversible.Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatography Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing.Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model.A yeast model for polyalanine-expansion aggregation and toxicity Sigma-1 receptor chaperones and diseases Aggregation kinetics of interrupted polyglutamine peptides Huntington's Disease and Striatal Signaling.Heat shock proteins as emerging therapeutic targets.NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy.Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease model Chaperones in autophagy.Heat shock proteins in the retina: Focus on HSP70 and alpha crystallins in ganglion cell survival.Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase Applying Hsp104 to protein-misfolding disorders.Molecular mechanisms and potential therapeutical targets in Huntington's disease.Huntington's disease, calcium, and mitochondria.Physical chemistry of polyglutamine: intriguing tales of a monotonous sequence.NMDA Receptor Activity in Neuropsychiatric Disorders.Association of heat-shock proteins in various neurodegenerative disorders: is it a master key to open the therapeutic door?Huntington's disease: from gene to potential therapy.Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104.Huntington's Disease: Mechanisms of Pathogenesis and Therapeutic Strategies.

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Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease.

http://www.wikidata.org/entity/Q35212735

description

2000 nî lūn-bûn

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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի օգոստոսին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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Bacterial and yeast chaperones ...... odels of Huntington's disease.

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Bacterial and yeast chaperones ...... odels of Huntington's disease.

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Bacterial and yeast chaperones ...... odels of Huntington's disease.

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Bacterial and yeast chaperones ...... odels of Huntington's disease.

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Bacterial and yeast chaperones ...... odels of Huntington's disease.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Bacterial and yeast chaperones ...... odels of Huntington's disease.

@en

P2093

Carmichael J

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Chatellier J

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Milstein C

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Rubinsztein DC

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Woolfson A

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P2860

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

Chaperone activity and structure of monomeric polypeptide binding domains of GroEL

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Abundant expression and cytoplasmic aggregations of [alpha]1A voltage-dependent calcium channel protein associated with neurodegeneration in spinocerebellar ataxia type 6

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

Glutamine repeats and neurodegenerative diseases: molecular aspects.

Intracellular inclusions, pathological markers in diseases caused by expanded polyglutamine tracts?

Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease.

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9701-9705

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10.1073/PNAS.170280697

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17

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97

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24448467

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10920207

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Huntington disease

molecular chaperones

P932

16928

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