Ligand-switchable substrates for a ubiquitin-proteasome system
about
Rapid and tunable control of protein stability in Caenorhabditis elegans using a small moleculeA method to rapidly create protein aggregates in living cells.Intracellular context affects levels of a chemically dependent destabilizing domainCRISPR/Cas9 allows efficient and complete knock-in of a destabilization domain-tagged essential protein in a human cell line, allowing rapid knockdown of protein functionDisordered proteinaceous machinesProtein misfolding specifies recruitment to cytoplasmic inclusion bodiesAn optimized, broadly applicable piggyBac transposon induction systemDestabilization domain approach adapted for regulated protein expression in the protozoan parasite Entamoeba histolytica.Heterologous expression of equine CYP3A94 and investigation of a tunable system to regulate co-expressed NADPH P450 oxidoreductase levels.Anchanling reduces pathology in a lactacystin- induced Parkinson's disease model.Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor ProteinsEngineering FKBP-Based Destabilizing Domains to Build Sophisticated Protein Regulation Systems.Distinct transcriptional responses elicited by unfolded nuclear or cytoplasmic protein in mammalian cells.A general strategy to construct small molecule biosensors in eukaryotes.Overhang polarity of chromosomal double-strand breaks impacts kinetics and fidelity of yeast non-homologous end joiningA Novel Destabilizing Domain Based on a Small-Molecule Dependent FluorophoreThe E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates.Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation.Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilizationProtein quality control system in neurodegeneration: a healing company hard to beat but failure is fatal.MAP Kinase Phosphatase 3 (MKP3) Preserves Norepinephrine Transporter Activity by Modulating ERK1/2 Kinase-Mediated Gene Expression.Substrate-induced protein stabilization reveals a predominant contribution from mature proteins to peptides presented on MHC class I.Chemogenetic Tools for Causal Cellular and Neuronal Biology.Drug-Inducible Control of Lethality Genes: A Low Background Destabilizing Domain Architecture Applied to the Gal4-UAS System in Drosophila.
P2860
Q27308937-57BBB528-CB37-4BCD-B634-32B5050F5450Q27315894-02664459-CAF6-46DB-935C-273E769505AFQ28483718-4B3D8ED1-407A-48DD-AF66-87C3ACAF5D3BQ28538004-CBB868AE-E49F-4089-977F-039F5D46CF18Q28652765-816260D5-A350-4E6E-B473-0EC56AF2EDE3Q30826780-259D3619-77AC-4C4E-A0A6-980BA0228E47Q33580353-7B6F6B72-AECA-4C37-8D18-57CBD324A75BQ34066946-C1CE1894-3BB1-42F0-B5D0-D9FAB12B704DQ34557281-281ED27C-1902-4480-BE2B-698729D585AAQ35157726-1089AFD8-77AC-4A55-9A93-56F49F021407Q35860705-39C40879-4189-4D79-BB93-984952C5986CQ35882019-C5715039-430F-4CE0-B4C0-89DDC265FFD1Q36049159-84C1AADB-3556-462B-AAD3-3D8108DA6AE2Q36539758-24AEBFBA-91CD-4CF7-A4E3-137427B76C6CQ36775535-320F4805-C209-4760-BBC9-0529303C04C5Q37192387-6A78A311-BECB-4168-9FE0-C7AFC30A774AQ37348923-EAB23AC0-C0B7-46D9-90D0-E138CCFE7FEDQ37583253-434D12FC-50E4-4BB6-AAE1-BDAF872A233BQ37661378-27F71444-0584-4D11-A956-BFEC24F484A5Q38078868-9209190D-2044-4725-B5B7-4142C53FE8C9Q41525327-6BC015E5-CCED-4774-A535-6113420B0427Q42174739-8D299795-DF44-4459-8C7A-F85A3177D393Q49917397-8ABFF0EE-9EDB-4987-9D5F-588D61A70998Q55397782-E2FAD3A2-8DB1-46D5-90D8-B096D88B5AF3
P2860
Ligand-switchable substrates for a ubiquitin-proteasome system
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Ligand-switchable substrates for a ubiquitin-proteasome system
@ast
Ligand-switchable substrates for a ubiquitin-proteasome system
@en
type
label
Ligand-switchable substrates for a ubiquitin-proteasome system
@ast
Ligand-switchable substrates for a ubiquitin-proteasome system
@en
prefLabel
Ligand-switchable substrates for a ubiquitin-proteasome system
@ast
Ligand-switchable substrates for a ubiquitin-proteasome system
@en
P2093
P2860
P356
P1476
Ligand-switchable substrates for a ubiquitin-proteasome system
@en
P2093
Corey W Liu
Emily L Egeler
Lorenz M Urner
Rishi Rakhit
Thomas J Wandless
P2860
P304
31328-31336
P356
10.1074/JBC.M111.264101
P407
P577
2011-07-15T00:00:00Z