Caspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress.
about
Adaptive and maladaptive expression of the mRNA regulatory protein HuRMultiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosisPhosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion.Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma.Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability.The RNA-binding protein RNPC1 stabilizes the mRNA encoding the RNA-binding protein HuR and cooperates with HuR to suppress cell proliferationHuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer CellsRNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC.Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer.miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth.Apoptotic-induced cleavage shifts HuR from being a promoter of survival to an activator of caspase-mediated apoptosisThe mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition.Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells.RNA-binding protein CELF1 promotes tumor growth and alters gene expression in oral squamous cell carcinoma.Inhibition of caspases protects mice from radiation-induced oral mucositis and abolishes the cleavage of RNA-binding protein HuR.Disruption of prostate epithelial differentiation pathways and prostate cancer development.Hypoxia reduces MAX expression in endothelial cells by unproductive splicing.Modulation of the mRNA-binding protein HuR as a novel reversal mechanism of epirubicin-triggered multidrug resistance in colorectal cancer cellsRosmarinic acid inhibits chemical hypoxia-induced cytotoxicity in primary cultured rat hepatocytes.Protective effect of dieckol against chemical hypoxia-induced cytotoxicity in primary cultured mouse hepatocytes.MYC and tumor metabolism: chicken and egg.Nitric oxide-heat shock protein axis in menopausal hot flushes: neglected metabolic issues of chronic inflammatory diseases associated with deranged heat shock response.Clinical Significance and Biological Role of HuR in Head and Neck Carcinomas.miR-291b-3p mediated ROS-induced endothelial cell dysfunction by targeting HUR
P2860
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P2860
Caspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
Caspase-mediated cleavage of R ...... pression after hypoxic stress.
@ast
Caspase-mediated cleavage of R ...... pression after hypoxic stress.
@en
type
label
Caspase-mediated cleavage of R ...... pression after hypoxic stress.
@ast
Caspase-mediated cleavage of R ...... pression after hypoxic stress.
@en
prefLabel
Caspase-mediated cleavage of R ...... pression after hypoxic stress.
@ast
Caspase-mediated cleavage of R ...... pression after hypoxic stress.
@en
P2093
P2860
P356
P1476
Caspase-mediated cleavage of R ...... xpression after hypoxic stress
@en
P2093
Brittany Carroll
Marion Boyd Gillespie
Sudha Talwar
P2860
P304
32333-32343
P356
10.1074/JBC.M111.255927
P407
P577
2011-07-27T00:00:00Z