The RNA-binding protein RNPC1 stabilizes the mRNA encoding the RNA-binding protein HuR and cooperates with HuR to suppress cell proliferation
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Adaptive and maladaptive expression of the mRNA regulatory protein HuRMultiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosisRNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.Krüppel -like factor 8 is a stress-responsive transcription factor that regulates expression of HuR.High expression of HuR in cytoplasm, but not nuclei, is associated with malignant aggressiveness and prognosis in bladder cancerMice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors.Poly (C)-binding protein 1 regulates p63 expression through mRNA stability.The RNA binding protein RBM38 (RNPC1) regulates splicing during late erythroid differentiation.Estrogen receptor (ER) was regulated by RNPC1 stabilizing mRNA in ER positive breast cancer.PPM1D phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38.RNA-binding Protein PCBP2 Regulates p73 Expression and p73-dependent Antioxidant DefenseThe role of c-Myc-RBM38 loop in the growth suppression in breast cancer.Disruption of prostate epithelial differentiation pathways and prostate cancer development.Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation.MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.Overexpression of the human antigen R suppresses the immediate paradoxical proliferation of melanoma cell subpopulations in response to suboptimal BRAF inhibition.Modulation of the p53 family network by RNA-binding proteins.The RNA-binding protein Rbm38 is dispensable during pressure overload-induced cardiac remodeling in micePTEN expression is upregulated by a RNA-binding protein RBM38 via enhancing its mRNA stability in breast cancer.RBM38 is involved in TGF-β-induced epithelial-to-mesenchymal transition by stabilising zonula occludens-1 mRNA in breast cancer.
P2860
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P2860
The RNA-binding protein RNPC1 stabilizes the mRNA encoding the RNA-binding protein HuR and cooperates with HuR to suppress cell proliferation
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2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
The RNA-binding protein RNPC1 ...... to suppress cell proliferation
@ast
The RNA-binding protein RNPC1 ...... to suppress cell proliferation
@en
type
label
The RNA-binding protein RNPC1 ...... to suppress cell proliferation
@ast
The RNA-binding protein RNPC1 ...... to suppress cell proliferation
@en
prefLabel
The RNA-binding protein RNPC1 ...... to suppress cell proliferation
@ast
The RNA-binding protein RNPC1 ...... to suppress cell proliferation
@en
P2093
P2860
P356
P1476
The RNA-binding protein RNPC1 ...... to suppress cell proliferation
@en
P2093
Seong-Jun Cho
Xinbin Chen
Yong-Sam Jung
P2860
P304
14535-14544
P356
10.1074/JBC.M111.326827
P407
P577
2012-02-27T00:00:00Z