Transcriptional activation of lysosomal exocytosis promotes cellular clearance. - Wikidata - awgldk - TriplyDB

Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

http://www.wikidata.org/entity/Q35214694

about

Glucocerebrosidase is shaking up the synucleinopathies Autophagy in lysosomal storage disorders The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction The crucial impact of lysosomes in aging and longevity Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis Sanfilippo syndrome: causes, consequences, and treatments The role of TRPMLs in endolysosomal trafficking and function Impairment of homeostasis in lysosomal storage disorders Permeation, regulation and control of expression of TRP channels by trace metal ions The endolysosomal system in cell death and survival The lysosome: from waste bag to potential therapeutic target Localized AL amyloidosis: a suicidal neoplasm?Regulation of lysosomal ion homeostasis by channels and transporters TFEB at a glance Transcriptional and epigenetic regulation of autophagy in aging Beyond indigestion: emerging roles for lysosome-based signaling in human disease Biphasic regulation of lysosomal exocytosis by oxidative stress Reprogramming of lysosomal gene expression by interleukin-4 and Stat6 A rapid and sensitive method for measuring N-acetylglucosaminidase activity in cultured cells A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis.mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases Lysosomal exocytosis and lipid storage disorders.Lysosomal adaptation: how the lysosome responds to external cues Time course of pathogenic and adaptation mechanisms in cystinotic mouse kidneys Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasis The phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activation Safety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders.Zn2+ efflux through lysosomal exocytosis prevents Zn2+-induced toxicity.Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis Pompe disease: from pathophysiology to therapy and back again Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes Signals from the lysosome: a control centre for cellular clearance and energy metabolism.Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB Lysosomal physiology.Lysosome: regulator of lipid degradation pathways.Oncogenic H-Ras up-regulates acid β-hexosaminidase by a mechanism dependent on the autophagy regulator TFEB

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P2860

Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

http://www.wikidata.org/entity/Q35214694

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

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Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

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Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

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Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

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Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

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Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

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J.DEVCEL.2011.07.016

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Developmental Cell

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Transcriptional activation of lysosomal exocytosis promotes cellular clearance.

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Alessandro Fraldi

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Antonella Pignata

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Carmine Spampanato

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Claudia Puri

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Gelsomina Mansueto

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Jose A Martina

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Marco Sardiello

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Michela Palmieri

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Roman Polishchuk

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Rosa Puertollano

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P2860

Cloning of the gene encoding a novel integral membrane protein, mucolipidin-and identification of the two major founder mutations causing mucolipidosis type IV

A gene network regulating lysosomal biogenesis and function

A block of autophagy in lysosomal storage disorders

Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes

TFEB links autophagy to lysosomal biogenesis

The biogenesis of lysosomes

Neuraminidase 1 is a negative regulator of lysosomal exocytosis

Mechanism of constitutive export from the golgi: bulk flow via the formation, protrusion, and en bloc cleavage of large trans-golgi network tubular domains.

Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.

Regulated secretion of conventional lysosomes.

P304

421-430

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scholarly article

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10.1016/J.DEVCEL.2011.07.016

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3

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21

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Diego Luis Medina

Fabio Annunziata

Andrea Ballabio

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2011-09-01T00:00:00Z

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51616718

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21889421

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3173716

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