Interdomain movements in metabotropic glutamate receptor activation.
about
Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulatorDistinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein couplingInvestigation of allosteric modulation mechanism of metabotropic glutamate receptor 1 by molecular dynamics simulations, free energy and weak interaction analysisStructural mechanism of ligand activation in human calcium-sensing receptor.Minireview: the intimate link between calcium sensing receptor trafficking and signaling: implications for disorders of calcium homeostasis.Structure and ligand recognition of class C GPCRsWhy is dimerization essential for class-C GPCR function? New insights from mGluR1 crystal structure analysis.Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptorsConformational dynamics of a class C G-protein-coupled receptorFunctional and pharmacological characteristics of metabotropic glutamate receptors 2/4 heterodimers.Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptorsAgonist-dependent signaling by group I metabotropic glutamate receptors is regulated by association with lipid domainsmGluR2 positive allosteric modulators: a patent review (2009 - present).Glutamate receptors in the kidney.Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.Organization and functions of mGlu and GABAB receptor complexes.Molecular determinants of positive allosteric modulation of the human metabotropic glutamate receptor 2.Glutamate acts as a partial inverse agonist to metabotropic glutamate receptor with a single amino acid mutation in the transmembrane domain.Differential modulation of the lactisole 'Sweet Water Taste' by sweeteners.N-glycosylation and disulfide bonding affects GPRC6A receptor expression, function, and dimerization.Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.Class C G protein-coupled receptors: reviving old couples with new partners.A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding.Structural biology of GABAB receptor.Activation of mGluR5 Attenuates Microglial Activation and Neuronal Apoptosis in Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats.Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy
P2860
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P2860
Interdomain movements in metabotropic glutamate receptor activation.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Interdomain movements in metabotropic glutamate receptor activation.
@ast
Interdomain movements in metabotropic glutamate receptor activation.
@en
type
label
Interdomain movements in metabotropic glutamate receptor activation.
@ast
Interdomain movements in metabotropic glutamate receptor activation.
@en
prefLabel
Interdomain movements in metabotropic glutamate receptor activation.
@ast
Interdomain movements in metabotropic glutamate receptor activation.
@en
P2093
P2860
P356
P1476
Interdomain movements in metabotropic glutamate receptor activation.
@en
P2093
Gilles Labesse
Jean-Philippe Pin
Jianfeng Liu
Jianhua Cao
Ming Jiang
Philippe Rondard
Siluo Huang
P2860
P304
15480-15485
P356
10.1073/PNAS.1107775108
P407
P577
2011-09-06T00:00:00Z