Dependence of cisplatin-induced cell death in vitro and in vivo on cyclin-dependent kinase 2
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Mechanisms of Cisplatin nephrotoxicityCisplatin-induced Kidney Dysfunction and Perspectives on Improving Treatment StrategiesTargeting Endogenous Repair Pathways after AKI.Protection of cisplatin cytotoxicity by an inactive cyclin-dependent kinase.HIF activation protects from acute kidney injury.Pathophysiology of cisplatin-induced acute kidney injury.Mitochondrial dysregulation and protection in cisplatin nephrotoxicity.Cdk2-dependent phosphorylation of p21 regulates the role of Cdk2 in cisplatin cytotoxicityIncreased expression of p21WAF1/CIP1 in kidney proximal tubules mediates fibrosis.Quercetin and Cisplatin combined treatment altered cell cycle and mitogen activated protein kinase expressions in malignant mesotelioma cells.Apoptosis and acute kidney injuryDNA damage response in cisplatin-induced nephrotoxicity.Cytoplasmic initiation of cisplatin cytotoxicity.A Comprehensive Review on the Genetic Regulation of Cisplatin-induced NephrotoxicityCdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak.Mimicking Cdk2 phosphorylation of Bcl-xL at Ser73 results in caspase activation and Bcl-xL cleavage.Cyclin-dependent kinase 2 signaling regulates myocardial ischemia/reperfusion injury.Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.The cell cycle and acute kidney injury.CDK4/6 inhibition induces epithelial cell cycle arrest and ameliorates acute kidney injury.Signalling mechanisms involved in renal pathological changes during cisplatin-induced nephropathy.Cell cycle control in the kidney.Overexpression of p18INK⁴C in LLC-PK1 cells increases resistance to cisplatin-induced apoptosis.Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells.DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex.Pkd1 haploinsufficiency increases renal damage and induces microcyst formation following ischemia/reperfusion.Urinary parameters predictive and electrolyte disturbances of cisplatin-induced acute renal associated with cancer as a critical target of the chemotherapeutic agent in patients with solid tumors.Involvement of the CDK2-E2F1 pathway in cisplatin cytotoxicity in vitro and in vivo.Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.Opposing roles of EGF in IFN-alpha-induced epithelial barrier destabilization and tissue repair.The deficiency of CX3CL1/CX3CR1 system ameliorates high fructose diet-induced kidney injury by regulating NF-κB pathways in CX3CR1-knock out mice.Exploring the Therapeutic Mechanism of Desmodium styracifolium on Oxalate Crystal-Induced Kidney Injuries Using Comprehensive Approaches Based on Proteomics and Network Pharmacology.The tumor suppressor role of miR-155-5p in gastric cancer.Immune mechanisms in the different phases of acute tubular necrosis
P2860
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P2860
Dependence of cisplatin-induced cell death in vitro and in vivo on cyclin-dependent kinase 2
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Dependence of cisplatin-induce ...... o on cyclin-dependent kinase 2
@ast
Dependence of cisplatin-induce ...... o on cyclin-dependent kinase 2
@en
type
label
Dependence of cisplatin-induce ...... o on cyclin-dependent kinase 2
@ast
Dependence of cisplatin-induce ...... o on cyclin-dependent kinase 2
@en
prefLabel
Dependence of cisplatin-induce ...... o on cyclin-dependent kinase 2
@ast
Dependence of cisplatin-induce ...... o on cyclin-dependent kinase 2
@en
P2093
P2860
P356
P1476
Dependence of cisplatin-induce ...... o on cyclin-dependent kinase 2
@en
P2093
Grazyna Nowak
Judit Megyesi
Peter M Price
Robert L Safirstein
P2860
P304
P356
10.1681/ASN.2006020162
P577
2006-08-16T00:00:00Z