HIF1alpha delays premature senescence through the activation of MIF. - Wikidata - awgldk - TriplyDB

HIF1alpha delays premature senescence through the activation of MIF.

HIF1alpha delays premature senescence through the activation of MIF.

http://www.wikidata.org/entity/Q35221154

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Molecular mechanisms of biological aging in intervertebral discs Macrophage migration inhibitory factor: a potential driver and biomarker for head and neck squamous cell carcinoma Role of macrophage migration inhibitory factor in age-related lung disease A multi-targeted approach to suppress tumor-promoting inflammation The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer.Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB Why is effective treatment of asthma so difficult? An integrated systems biology hypothesis of asthma Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction.Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart Role of notch signaling in the maintenance of human mesenchymal stem cells under hypoxic conditions.Down-regulation of MIF by NFκB under hypoxia accelerated neuronal loss during stroke.Hypoxia, melanocytes and melanoma - survival and tumor development in the permissive microenvironment of the skin.Identification of a novel cell type-specific intronic enhancer of macrophage migration inhibitory factor (MIF) and its regulation by mithramycin.Development of lymphoproliferative diseases by hypoxia inducible factor-1alpha is associated with prolonged lymphocyte survival.Stromal-dependent tumor promotion by MIF family members.The importance of mitochondrial DNA in aging and cancer.Hypoxia-inducible factor-1α regulates the expression of genes in hypoxic hepatic stellate cells important for collagen deposition and angiogenesis.MIF family members cooperatively inhibit p53 expression and activity The role of hypoxia inducible factor-1 alpha in bypassing oncogene-induced senescence Hypoxia induces an undifferentiated phenotype of oral keratinocytes in vitro Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL.Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression.Novel ARF/p53-independent senescence pathways in cancer repression.HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes.Macrophage migration inhibitory factor mediates hypoxia-induced pulmonary hypertension.Macrophage Migration Inhibitory Factor Secretion Is Induced by Ionizing Radiation and Oxidative Stress in Cancer Cells.Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia Steroid receptor coactivator 3 regulates autophagy in breast cancer cells through macrophage migration inhibitory factor Matters of life and breath: A role for hypoxia in determining cell state.Negative regulation of AMP-activated protein kinase (AMPK) activity by macrophage migration inhibitory factor (MIF) family members in non-small cell lung carcinomas Macrophage migration inhibitory factor produced by the tumour stroma but not by tumour cells regulates angiogenesis in the B16-F10 melanoma model.A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype O2 sensing, mitochondria and ROS signaling: The fog is lifting HIF-1: an age-dependent regulator of lens cell proliferation.Macrophage migration inhibitory factor manipulation and evaluation in tumoral hypoxic adaptation.

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P2860

HIF1alpha delays premature senescence through the activation of MIF.

http://www.wikidata.org/entity/Q35221154

description

2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

HIF1alpha delays premature senescence through the activation of MIF.

@ast

HIF1alpha delays premature senescence through the activation of MIF.

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type

label

HIF1alpha delays premature senescence through the activation of MIF.

@ast

HIF1alpha delays premature senescence through the activation of MIF.

@en

prefLabel

HIF1alpha delays premature senescence through the activation of MIF.

@ast

HIF1alpha delays premature senescence through the activation of MIF.

@en

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Genes & Development

P1476

HIF1alpha delays premature senescence through the activation of MIF.

@en

P2093

Amato J Giaccia

http://www.w3.org/2001/XMLSchema#string

Barbara Bedogni

http://www.w3.org/2001/XMLSchema#string

Katarina Gradin

http://www.w3.org/2001/XMLSchema#string

Lorenz Poellinger

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Marianne Broome Powell

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Scott M Welford

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P2860

A proinflammatory cytokine inhibits p53 tumor suppressor activity

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Induction of human endometrial cancer cell senescence through modulation of HIF-1alpha activity by EGLN1

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha

The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

Production of high-titer helper-free retroviruses by transient transfection

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3366-3371

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10.1101/GAD.1471106

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24

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20

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1698444

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