Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation
about
Discs Large Homolog 1 Splice Variants Regulate p38-Dependent and -Independent Effector Functions in CD8+ T Cells.Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.Chromatin decondensation and T cell hyperresponsiveness in diabetes-associated hyperglycemia.Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects.Counter-regulation of T cell effector function by differentially activated p38.The p38β mitogen-activated protein kinase possesses an intrinsic autophosphorylation activity, generated by a short region composed of the α-G helix and MAPK insert.Selective phosphorylation of the Dlg1AB variant is critical for TCR-induced p38 activation and induction of proinflammatory cytokines in CD8+ T cells.Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitisSignaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammationMechanism for p38α-mediated experimental autoimmune encephalomyelitis.Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK.Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2.GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis.Activation of p38α in T cells regulates the intestinal host defense against attaching and effacing bacterial infectionsGene Expression Profiles Underlying Selective T-Cell-Mediated Immunity Activity of a Chinese Medicine Granule on Mice Infected with Influenza Virus H1N1.Sex-specific control of central nervous system autoimmunity by p38 mitogen-activated protein kinase signaling in myeloid cells.Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell InductionDendritic cell MST1 inhibits Th17 differentiation.The emerging role of p38 mitogen-activated protein kinase in multiple sclerosis and its models.Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer.The p38 mitogen-activated protein kinase cascade modulates T helper type 17 differentiation and functionality in multiple sclerosis.Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice.Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation.p38α regulates cytokine-induced IFNγ secretion via the Mnk1/eIF4E pathway in Th1 cells.Stress-Activated Protein Kinases in Spinal Cord Injury: Focus on Roles of p38.
P2860
Q30009140-3DDB1935-E415-4B3A-B46B-B99FA25740A8Q30384798-68506B87-8219-4E61-8268-826CB3A7A9C9Q30601364-F6986384-C929-4CB2-8221-C1FCF21A8716Q30821888-AC262D98-6CE8-4581-843D-401A66A10659Q33702970-00C9FB9B-C7D2-4742-926C-C0F4B6CFB0D0Q34140902-9DCA2B66-649D-4E0A-A852-13BA6B8B89F4Q34150054-03CBA8C9-616B-429F-B7D3-C84021734762Q35230209-58A8FFAB-ED9C-4A81-AA7E-11B6C8412EA6Q35685580-EE94E9E9-2B98-47B9-B2D2-9420D863050EQ36097933-255BD2BF-7C94-49F1-A22C-987A5AB0F80BQ36421693-5935D761-02F9-41B5-851B-48DC46C32014Q36757169-5099D4E6-97FA-421A-A77B-D36B4AADFCF4Q36962357-D71A5B7C-D39C-43B6-BE19-CA8AA7963656Q37163776-B0D20D80-A689-4593-AAAE-54E3E6F3BB6AQ37543279-EC3B0817-3822-4F60-821B-D64CE12BECBFQ37622868-08F58619-A305-4009-89E0-330ADD281296Q37623379-B0799DC3-8DDD-48DD-AD3F-7EBFDA57764BQ37630340-B8CC8E78-9D53-4308-8F92-9878F591AAE4Q38125129-EFAF3A5A-52B6-4DFA-84C4-A4086D9F9530Q38366515-692640F5-0B27-4A80-AA4A-4FAACD293D7FQ40815617-0522B3CE-00FD-4309-A773-D52D080B8D7CQ47135902-061660FD-39BE-4275-B3DE-3CD7975BE53DQ48193369-356C8426-2FBD-4BBF-BB42-4197A835E24CQ50946132-C541AFEF-E663-43C9-8317-4479BEF2D8A8Q54121159-1865CB6D-9B36-43D6-8573-4DD8DE7ED21F
P2860
Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Lack of the T cell-specific al ...... autoimmunity and inflammation
@ast
Lack of the T cell-specific al ...... autoimmunity and inflammation
@en
type
label
Lack of the T cell-specific al ...... autoimmunity and inflammation
@ast
Lack of the T cell-specific al ...... autoimmunity and inflammation
@en
prefLabel
Lack of the T cell-specific al ...... autoimmunity and inflammation
@ast
Lack of the T cell-specific al ...... autoimmunity and inflammation
@en
P2093
P2860
P1433
P1476
Lack of the T cell-specific al ...... autoimmunity and inflammation
@en
P2093
Jonathan D Ashwell
Ludmila Jirmanova
Maria Letizia Giardino Torchia
Nandakumara D Sarma
Paul R Mittelstadt
P2860
P304
P356
10.1182/BLOOD-2011-01-333039
P407
P577
2011-06-28T00:00:00Z