Beneficial role of Nrf2 in regulating NADPH generation and consumption. - Wikidata - awgldk - TriplyDB

Beneficial role of Nrf2 in regulating NADPH generation and consumption.

Beneficial role of Nrf2 in regulating NADPH generation and consumption.

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Keap1/Nrf2 pathway in the frontiers of cancer and non-cancer cell metabolism The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics Biochemical basis of the antidiabetic activity of oleanolic acid and related pentacyclic triterpenes TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO Nuclear Factor-Erythroid-2-Related Factor 2 in Aging and Lung Fibrosis Reactive oxygen production induced by the gut microbiota: pharmacotherapeutic implications Dichlorvos exposure results in large scale disruption of energy metabolism in the liver of the zebrafish, Danio rerio Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver Implementation of a high-throughput screen for identifying small molecules to activate the Keap1-Nrf2-ARE pathway Tissue distribution, ontogeny, and chemical induction of aldo-keto reductases in mice Nrf2 pathway activation contributes to anti-fibrosis effects of ginsenoside Rg1 in a rat model of alcohol- and CCl4-induced hepatic fibrosis.Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion.Dietary regulation of Keap1/Nrf2/ARE pathway: focus on plant-derived compounds and trace minerals.Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks.Nrf2 affects the efficiency of mitochondrial fatty acid oxidation.Redox-based therapeutics in neurodegenerative disease.Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice.Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae.Deficiency in Nrf2 transcription factor decreases adipose tissue mass and hepatic lipid accumulation in leptin-deficient mice Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1.Overexpression of Nrf2 protects against microcystin-induced hepatotoxicity in mice.Lutein has a protective effect on hepatotoxicity induced by arsenic via Nrf2 signaling.Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.Docosahexaenoic (DHA) modulates phospholipid-hydroperoxide glutathione peroxidase (Gpx4) gene expression to ensure self-protection from oxidative damage in hippocampal cells Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney.Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells NRF2 and the Phase II Response in Acute Stress Resistance Induced by Dietary Restriction.Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet.Nrf2 protection against liver injury produced by various hepatotoxicants.Nrf2: a potential target for new therapeutics in liver disease.Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration.Keap1 knockdown increases markers of metabolic syndrome after long-term high fat diet feeding The Role of Sulfhydryl Reactivity of Small Molecules for the Activation of the KEAP1/NRF2 Pathway and the Heat Shock Response Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming.Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress.Molecular and chemical regulation of the Keap1-Nrf2 signaling pathway.The role of the Nrf2/Keap1 pathway in obesity and metabolic syndrome.The emerging role of Nrf2 in mitochondrial function

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Beneficial role of Nrf2 in regulating NADPH generation and consumption.

http://www.wikidata.org/entity/Q35231072

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Beneficial role of Nrf2 in regulating NADPH generation and consumption.

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Beneficial role of Nrf2 in regulating NADPH generation and consumption.

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Beneficial role of Nrf2 in regulating NADPH generation and consumption.

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Beneficial role of Nrf2 in regulating NADPH generation and consumption.

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Beneficial role of Nrf2 in regulating NADPH generation and consumption.

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Beneficial role of Nrf2 in regulating NADPH generation and consumption.

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Toxicological Sciences

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Beneficial role of Nrf2 in regulating NADPH generation and consumption.

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Curtis D Klaassen

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Julia Yue Cui

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Kai Connie Wu

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P2860

Fatty acid synthesis: a potential selective target for antineoplastic therapy

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

Biochemical effects of SIRT1 activators

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

Bilirubin is an antioxidant of possible physiological importance

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

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590-600

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10.1093/TOXSCI/KFR183

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2

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21775727

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