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Genes and pathophysiology of type 2 diabetes: more than just the Randle cycle all over againObesity and cancer, a case for insulin signalingThe Diagnosis and Management of Hyperinsulinaemic HypoglycaemiaThe Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cellsAutoantibodies against CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) that impair glucose-induced insulin secretion in noninsulin- dependent diabetes patientsRILM: a web-based resource to aid comparative and functional analysis of the insulin and IGF-1 receptor family.Forward chemical genetic approach identifies new role for GAPDH in insulin signaling.Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications.Homozygosity for a new mutation (Ile119-->Met) in the insulin receptor gene in five sibs with familial insulin resistanceInsulin receptor activation with transmembrane domain ligands.Hyperinsulinemia is associated with altered insulin receptor mRNA splicing in muscle of the spontaneously obese diabetic rhesus monkey.Insulin receptor variant forms and type 2 diabetes mellitus.Genetic insulin resistance is a potent regulator of gene expression and proliferation in human iPS cellsFounder effect in the Horn of Africa for an insulin receptor mutation that may impair receptor recyclingReducing IRS-1 Activation Cause Mutation of Tyrosine Kinase Domain hINSR Gene on Type-2 Diabetes Mellitus Patients.Lifespan and glucose metabolism in insulin receptor mutant mice.SNP analysis of follistatin gene associated with polycystic ovarian syndromeState of the Art Review: Emerging Therapies: The Use of Insulin Sensitizers in the Treatment of Adolescents with Polycystic Ovary Syndrome (PCOS).Tyrosine kinase-deficient mutant human insulin receptors (Met1153-->Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4.Thirty-seven candidate genes for polycystic ovary syndrome: strongest evidence for linkage is with follistatinExcessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome.Association of the insulin-receptor variant Met-985 with hyperglycemia and non-insulin-dependent diabetes mellitus in the Netherlands: a population-based study.Clustering of genetically defined allele classes in the Caenorhabditis elegans DAF-2 insulin/IGF-1 receptor.Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus.Enhancement or inhibition of insulin signaling by insulin receptor substrate 1 is cell context dependent.Perspectives in Polycystic Ovary Syndrome: From Hair to EternityGenetics of the polycystic ovary syndrome.Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosisLoss of NPC1 function in a patient with a co-inherited novel insulin receptor mutation does not grossly modify the severity of the associated insulin resistance.Successful pregnancy outcomes in a patient with type A insulin resistance syndrome.Human diabetes associated with defects in nuclear regulatory proteins for the insulin receptor gene.Impaired activation of phosphoinositide 3-kinase by insulin in fibroblasts from patients with severe insulin resistance and pseudoacromegaly. A disorder characterized by selective postreceptor insulin resistance.Caenorhabditis elegans DAF-2 as a Model for Human Insulin Receptoropathies.Investigation of the mechanism of the dominant negative effect of mutations in the tyrosine kinase domain of the insulin receptor.Low-frequency variants in HMGA1 are not associated with type 2 diabetes riskElevated protein tyrosine phosphatase activity and increased membrane viscosity are associated with impaired activation of the insulin receptor kinase in old ratsBody composition and regional fat distribution in polycystic ovarian syndrome. Relationship to hormonal and metabolic profiles.
P2860
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P2860
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Mutations in the insulin receptor gene.
@ast
Mutations in the insulin receptor gene.
@en
type
label
Mutations in the insulin receptor gene.
@ast
Mutations in the insulin receptor gene.
@en
prefLabel
Mutations in the insulin receptor gene.
@ast
Mutations in the insulin receptor gene.
@en
P2093
P356
P1433
P1476
Mutations in the insulin receptor gene.
@en
P2093
Barbetti F
Levy-Toledano R
Wertheimer E
de la Luz Sierra M
P304
P356
10.1210/ER.13.3.566
P577
1992-08-01T00:00:00Z