Separation of lytic and transforming functions of the simian virus 40 A region: two mutants which are temperature sensitive for lytic functions have opposite effects on transformation.
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Induction of duplication reversion in human fibroblasts, by wild-type and mutated SV40 T antigen, covaries with the ability to induce host DNA synthesis.Mapping of phosphomonoester and apparent phosphodiester bonds of the oncogene product p53 from simian virus 40-transformed 3T3 cells.Integration and expression of a truncated simian virus 40 early gene fragment in mammalian cellsFragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells.Species-specific phosphorylation of mouse and rat p53 in simian virus 40-transformed cells.Helicase, DNA-binding, and immunological properties of replication-defective simian virus 40 mutant T antigens.Large T-antigen mutants define multiple steps in the initiation of simian virus 40 DNA replicationTwo separable functional domains of simian virus 40 large T antigen: carboxyl-terminal region of simian virus 40 large T antigen is required for efficient capsid protein synthesis.Characterization of a new simian virus 40 mutant, tsA3900, isolated from deletion mutant tsA1499.Mutations near the carboxyl terminus of the simian virus 40 large tumor antigen alter viral host rangeNonviable mutants of simian virus 40 with deletions near the 3' end of gene A define a function for large T antigen required after onset of viral DNA replication.A functional simian virus 40 origin of replication is required for the generation of a super T antigen with a molecular weight of 100,000 in transformed mouse cells.Deletion and insertion mutations in early region 1a of type 5 adenovirus that produce cold-sensitive or defective phenotypes for transformation.Construction and characterization of viable deletion mutants of simian virus 40 lacking sequences near the 3' end of the early region.Functional analysis of a simian virus 40 super T-antigenImproved localization of phosphorylation sites in simian virus 40 large T antigen.Study of the functional activities concomitantly retained by the 115,000 Mr super T antigen, an evolutionary variant of simian virus 40 large T antigen expressed in transformed rat cells.Mutant of simian virus 40 large T-antigen that is defective for viral DNA synthesis, but competent for transformation of cultured rat cellsAssociation of simian virus 40 T antigen with the nuclear matrix of infected and transformed monkey cells.Nonlytic simian virus 40-specific 100K phosphoprotein is associated with anchorage-independent growth in simian virus 40-transformed and revertant mouse cell lines.DNA-binding properties of simian virus 40 T-antigen mutants defective in viral DNA replication.Deletion of 43 amino acids in the NH2-terminal half of the large tumor antigen of simian virus 40 results in a non-karyophilic protein capable of transforming established cells.Simian virus 40 small t antigen activates the carboxyl-terminal transforming p53-binding domain of large T antigen.Analysis of simian virus 40 small t antigen-induced progression of rat F111 cells minimally transformed by large T antigen.Phenotype-specific phosphorylation of simian virus 40 tsA mutant large T antigens in tsA N-type and A-type transformants.Functional implications of oligomerization of simian virus 40 large T antigen during lytic virus infection.Resolution of a polyomavirus-mouse hybrid replicon: viral function required for recombination.Oligomerization of simian virus 40 large T antigen is not necessarily repressed by temperature-sensitive A gene lesions.Large-T-antigen-p53 complex formation is not cold sensitive in a cold-sensitive transformant induced by simian virus 40 mutant tsA1499.Cold-sensitive growth of simian virus 40 in semipermissive variants of CV1 cells.Evidence for free and metabolically stable p53 protein in nuclear subfractions of simian virus 40-transformed cells.Independent expression of the transforming amino-terminal domain of SV40 large I antigen from an alternatively spliced third SV40 early mRNA.Structural prerequisites of simian virus 40 large T antigen for the maintenance of cell transformation
P2860
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P2860
Separation of lytic and transforming functions of the simian virus 40 A region: two mutants which are temperature sensitive for lytic functions have opposite effects on transformation.
description
1981 nî lūn-bûn
@nan
1981 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1981 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
name
Separation of lytic and transf ...... ite effects on transformation.
@ast
Separation of lytic and transf ...... ite effects on transformation.
@en
type
label
Separation of lytic and transf ...... ite effects on transformation.
@ast
Separation of lytic and transf ...... ite effects on transformation.
@en
prefLabel
Separation of lytic and transf ...... ite effects on transformation.
@ast
Separation of lytic and transf ...... ite effects on transformation.
@en
P2093
P2860
P1433
P1476
Separation of lytic and transf ...... site effects on transformation
@en
P2093
P2860
P304
P407
P577
1981-05-01T00:00:00Z