Structural prerequisites of simian virus 40 large T antigen for the maintenance of cell transformation - Wikidata - awgldk - TriplyDB

Structural prerequisites of simian virus 40 large T antigen for the maintenance of cell transformation

Structural prerequisites of simian virus 40 large T antigen for the maintenance of cell transformation

http://www.wikidata.org/entity/Q41428303

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Thermally inactivated simian virus 40 tsA58 mutant T antigen cannot initiate viral DNA replication in vitro Replication and transformation functions of in vitro-generated simian virus 40 large T antigen mutants Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex Functional role of BK virus tumor antigens in transformation Overproduction of protein p53 contributes to simian virus 40-mediated transformation.Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines.Simian virus 40 small t antigen activates the carboxyl-terminal transforming p53-binding domain of large T antigen.Primary rat cells expressing a hybrid polyomavirus-simian virus 40 large T antigen have altered growth properties.Two conditional tsA mutant simian virus 40 T antigens display marked differences in thermal inactivation.Oligomerization of oncoprotein p53.Dimers and complexes with p53 are the prevalent oligomeric forms of a transforming nonkaryophilic T antigen of simian virus 40.Complex formation of simian virus 40 large T antigen with cellular protein p53.

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Structural prerequisites of simian virus 40 large T antigen for the maintenance of cell transformation

http://www.wikidata.org/entity/Q41428303

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1985 nî lūn-bûn

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1985年論文

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J.1460-2075.1985.TB04027.X

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The EMBO Journal

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Structural prerequisites of si ...... tenance of cell transformation

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Aggeler G

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Henning R

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Kohler M

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Montenarh M

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A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels

T antigen is bound to a host protein in SV40-transformed cells

Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens

Detection and characterization of multiple forms of simian virus 40 large T antigen

Complex of simian virus 40 large-T antigen and host 53,000-molecular-weight protein in monkey cells.

Separation of lytic and transforming functions of the simian virus 40 A region: two mutants which are temperature sensitive for lytic functions have opposite effects on transformation.

Complex of simian virus 40 large tumor antigen and 48,000-dalton host tumor antigen

Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen

Microinjection of monoclonal antibody to protein p53 inhibits serum-induced DNA synthesis in 3T3 cells.

Function of simian virus 40 gene A in transforming infection.

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2941-2947

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