Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells - Wikidata - awgldk - TriplyDB

Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells

Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells

http://www.wikidata.org/entity/Q35238060

about

Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism.uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies.The interconnectedness of cancer cell signaling.Chick chorioallantoic membrane (CAM) assay as an in vivo model to study the effect of newly identified molecules on ovarian cancer invasion and metastasis.EGFR regulates the development and microarchitecture of intratumoral angiogenic vasculature capable of sustaining cancer cell intravasation.Protumorigenic activity of plasminogen activator inhibitor-1 through an antiapoptotic function Tumor MMP-1 activates endothelial PAR1 to facilitate vascular intravasation and metastatic dissemination Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer.Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature.Cancer subclonal genetic architecture as a key to personalized medicine.Evaluation of 12-lipoxygenase (12-LOX) and plasminogen activator inhibitor 1 (PAI-1) as prognostic markers in prostate cancer.Cell surface remodeling by plasmin: a new function for an old enzyme.Tumor cell intravasation.INPP4B suppresses prostate cancer cell invasion In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling Preclinical evaluation of [111 In]MICA-401, an activity-based probe for SPECT imaging of in vivo uPA activity.Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10.Zebrafish Xenograft: An Evolutionary Experiment in Tumour Biology.Overcoming intratumor heterogeneity of polygenic cancer drug resistance with improved biomarker integration Overexpression of forkhead box M1 and urokinase-type plasminogen activator in gastric cancer is associated with cancer progression and poor prognosis.Decreased methylation in the SNAI2 and ADAM23 genes associated with de-differentiation and haematogenous dissemination in breast cancers

P2860

Q34434875-AFEFCC3D-02E6-47DB-9D44-59B66DF9D919 Q35580701-B107D1A6-84E3-4DC4-8ECC-BF91E148118A Q35669733-28DDE75B-C12A-4C85-BD9C-CA8BBD7B3F49 Q36202406-4010CF49-DE00-4A10-BC34-C400405A60F7 Q36360133-DFED885B-B739-4FCF-A2DB-609D049C3E13 Q36486880-399DFD8C-21FB-48DC-86D0-5B4520D616A0 Q37125854-5A690DD2-6D71-4090-AA8F-DB00C3733C66 Q37131462-8C22D7E2-0C6F-4468-A7FA-A1742624052D Q37364878-41138CC8-6F1B-4B32-8982-181572CE2704 Q37448116-EEBAC0EA-93EE-4813-BD85-AC0BCCE62F91 Q37695659-CA2DC491-E6F5-4704-AF27-29F12073A196 Q38055477-D2A1268A-E030-4148-ACE1-CD037C483687 Q38807918-6FF84AB1-1E94-4A37-85FB-5E349B415ADC Q38953956-32FA4973-209D-40F6-AAC2-9A66B53E4CBF Q39233213-9A2D9A3F-2C42-4347-BA49-1D8939853CB7 Q39456396-3C1C27C6-13E5-4FE2-A9E6-A3D1D2FE75B7 Q40860086-B29401BB-9728-4EF8-AA7A-17995E9AF0AE Q41673632-470E66BA-3600-476D-A0ED-3CF7AC68B014 Q41879186-2E17C8D7-73FC-4DEA-B77F-E49B703020F7 Q47654322-957CA26B-6722-4475-B1C3-D66E7748F824 Q58761810-72F3CF82-D380-4915-AB5E-39989DE0B627

P2860

Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells

http://www.wikidata.org/entity/Q35238060

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Activation of pro-uPA is criti ...... ation of human carcinoma cells

@ast

Activation of pro-uPA is criti ...... ation of human carcinoma cells

@en

type

label

Activation of pro-uPA is criti ...... ation of human carcinoma cells

@ast

Activation of pro-uPA is criti ...... ation of human carcinoma cells

@en

prefLabel

Activation of pro-uPA is criti ...... ation of human carcinoma cells

@ast

Activation of pro-uPA is criti ...... ation of human carcinoma cells

@en

P1433

Q35238060-F6822927-6883-4E21-B828-EAA7D90CCFD7

P1476

Q35238060-848274C4-6045-44B9-8CE0-0963586A468E

P2093

Q35238060-1F20300E-A409-4D32-813F-A849D4882C60

Q35238060-341BA5D3-F8CE-45D2-A985-66A1AF12DE80

Q35238060-67058957-2FE7-4A5A-8919-9877A0B89DEA

Q35238060-6CB1B36A-6557-445E-8AEB-A623B2317BDE

Q35238060-9CB71034-C298-45DA-B08E-E6BB29B82F91

Q35238060-C2CEAD22-441B-49EE-997B-BA46EDDE3B10

Q35238060-C9F4E6F7-08F2-478F-A197-6ADA161636EA

P2860

Q35238060-05D9E1D2-B64A-4D79-AF5D-12654A681135

Q35238060-113288AE-C06D-435D-954C-5A299625F349

Q35238060-1501DF51-2F52-4216-9C38-12C6AAFAF6F1

Q35238060-15B0D862-B9E5-4F12-91D6-7729716E9E72

Q35238060-1DB2BF8A-97BF-4F1B-A442-31D60F6D8D27

Q35238060-22B1D8CD-2343-46F1-842D-E384FF621A20

Q35238060-26449B17-9878-4CEF-96A9-A5BDEC505213

Q35238060-3A094673-C329-4D07-B49A-BF8DBC425F0B

Q35238060-3C0A97DD-3AD0-4D51-97AB-4D4D92CB41FF

Q35238060-4042EA56-8B80-4183-AF89-3A30323B90C5

P304

Q35238060-C45CC51D-92FF-4AA2-8FE8-36EA9AFB8A26

P31

Q35238060-8A10D7DF-0A03-4222-95A9-50D05B764991

P356

Q35238060-78C9AFB3-377B-4147-B575-D2B32A62B8F5

P433

Q35238060-3A1AA1CE-0014-48D6-BCE1-873A715CA202

P478

Q35238060-0609733C-5E5B-4E84-B355-B9AE82FFAE7A

P577

Q35238060-A15900C3-3642-48BC-9CA1-DE3452AD5725

P5875

Q35238060-603171FE-B86E-4A3C-965D-F0BF42D4DC8D

P698

Q35238060-F11A6406-FE27-4528-AADB-70310479FDC4

P932

Q35238060-BD870E95-19D4-4AFF-9CF1-675DAF445AFF

P356

P1433

P1476

Activation of pro-uPA is criti ...... ation of human carcinoma cells

@en

P2093

Elena I Deryugina

http://www.w3.org/2001/XMLSchema#string

Erin M Bekes

http://www.w3.org/2001/XMLSchema#string

Ewa Zajac

http://www.w3.org/2001/XMLSchema#string

James P Quigley

http://www.w3.org/2001/XMLSchema#string

Kenneth A Botkjaer

http://www.w3.org/2001/XMLSchema#string

Peter A Andreasen

http://www.w3.org/2001/XMLSchema#string

Tatyana A Kupriyanova

http://www.w3.org/2001/XMLSchema#string

P2860

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

Pro-urokinase-type plasminogen activator is a substrate for hepsin

RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo

Deadly allies: the fatal interplay between platelets and metastasizing cancer cells

Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion

Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease

A plasma kallikrein-dependent plasminogen cascade required for adipocyte differentiation

Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activation

Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor

Matrix metalloproteinases: regulators of the tumor microenvironment

P304

806-821

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1593/NEO.11704

http://www.w3.org/2001/XMLSchema#string

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

13

http://www.w3.org/2001/XMLSchema#string

P577

2011-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51691469

http://www.w3.org/2001/XMLSchema#string

P698

21969814

http://www.w3.org/2001/XMLSchema#string

P932

3182273

http://www.w3.org/2001/XMLSchema#string