Protumorigenic activity of plasminogen activator inhibitor-1 through an antiapoptotic function
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Plasminogen Activator Inhibitor-1 in Cancer: Rationale and Insight for Future Therapeutic TestinguPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy.Expression of Bmi-1 and PAI-1 in esophageal squamous cell carcinomaMatrix metalloproteinase-10 promotes tumor progression through regulation of angiogenic and apoptotic pathways in cervical tumors.PAI-1 leads to G1-phase cell-cycle progression through cyclin D3/cdk4/6 upregulationmiR-30b, down-regulated in gastric cancer, promotes apoptosis and suppresses tumor growth by targeting plasminogen activator inhibitor-1.Serpins promote cancer cell survival and vascular co-option in brain metastasisTargeting plasminogen activator inhibitor-1 inhibits angiogenesis and tumor growth in a human cancer xenograft model.A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavageuPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies.Small Molecule Inhibitors of Plasminogen Activator Inhibitor-1 Elicit Anti-Tumorigenic and Anti-Angiogenic Activity.Intracellular Expression of PAI-1 Specific Aptamers Alters Breast Cancer Cell Migration, Invasion and Angiogenesis.Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer.Enhanced cell migration and apoptosis resistance may underlie the association between high SERPINE1 expression and poor outcome in head and neck carcinoma patients.Bilateral ovarian carcinomas differ in the expression of metastasis-related genesPAI-1 and HER2 interaction in advanced breast cancer disease: evidence for added benefit from trastuzumab in HER2-negative patients.Targeted Inhibition of PAI-1 Activity Impairs Epithelial Migration and Wound Closure Following Cutaneous Injury.Small Molecule Targeting of PAI-1 Function: A New Therapeutic Approach for Treatment of Vascular StenosisConditional Knockdown of Gene Expression in Cancer Cell Lines to Study the Recruitment of Monocytes/Macrophages to the Tumor Microenvironment.SK-216, a Novel Inhibitor of Plasminogen Activator Inhibitor-1, Suppresses Lung Metastasis of Human Osteosarcoma.High glucose and insulin enhance uPA expression, ROS formation and invasiveness in breast cancer-derived cells.The crosstalk between breast carcinoma-associated fibroblasts and cancer cells promotes RhoA-dependent invasion via IGF-1 and PAI-1.Diabetes-associated dysregulated cytokines and cancer.
P2860
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P2860
Protumorigenic activity of plasminogen activator inhibitor-1 through an antiapoptotic function
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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name
Protumorigenic activity of pla ...... ough an antiapoptotic function
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Protumorigenic activity of pla ...... ough an antiapoptotic function
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type
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Protumorigenic activity of pla ...... ough an antiapoptotic function
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Protumorigenic activity of pla ...... ough an antiapoptotic function
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prefLabel
Protumorigenic activity of pla ...... ough an antiapoptotic function
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Protumorigenic activity of pla ...... ough an antiapoptotic function
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P2860
P356
P1476
Protumorigenic activity of pla ...... ough an antiapoptotic function
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P2093
Veronica R Placencio
P2860
P304
P356
10.1093/JNCI/DJS377
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P50
P577
2012-09-13T00:00:00Z