The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice
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Role of bile acids in the regulation of the metabolic pathwaysBile acid receptors and nonalcoholic fatty liver diseaseBile Acid Metabolism and Signaling in Cholestasis, Inflammation, and CancerXenobiotic and Endobiotic Mediated Interactions Between the Cytochrome P450 System and the Inflammatory Response in the LiverBile acid metabolism and signalingGut Microbiota and Host Reaction in Liver DiseasesKey discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decadesBile acid signaling in metabolic disease and drug therapyIdentification of miR-26a as a target gene of bile acid receptor GPBAR-1/TGR5Cystic fibrosis related liver disease--another black box in hepatology.Commensal bacteria at the interface of host metabolism and the immune system.The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice.A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading.Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer.Bile acid signaling and liver regeneration.Non alcoholic steatohepatitis a precursor for hepatocellular carcinoma development.Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3.TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translationGPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells.Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.Emerging science of the human microbiome.Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.Systematic review: bile acids and intestinal inflammation-luminal aggressors or regulators of mucosal defence?Functions of innate immune cells and commensal bacteria in gut homeostasis.Microbial transmission from mothers with obesity or diabetes to infants: an innovative opportunity to interrupt a vicious cycle.TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.Early Increases in Bile Acids Post Roux-en-Y Gastric Bypass Are Driven by Insulin-Sensitizing, Secondary Bile Acids.Advances in pharmacotherapy for primary biliary cirrhosis.Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liverPreference of Conjugated Bile Acids over Unconjugated Bile Acids as Substrates for OATP1B1 and OATP1B3.The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling PathwayLithocholic acid controls adaptive immune responses by inhibition of Th1 activation through the Vitamin D receptor.Discovery of a Potent and Orally Efficacious TGR5 Receptor Agonist.The G-protein-coupled bile acid receptor Gpbar1 (TGR5) suppresses gastric cancer cell proliferation and migration through antagonizing STAT3 signaling pathwayBile Acid Receptors and Liver Cancer.The TGR5 receptor mediates bile acid-induced itch and analgesiaTGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's diseaseMechanisms of oxysterol-induced disease: insights from the biliary system.Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease.
P2860
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P2860
The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice
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2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The G-protein-coupled bile aci ...... ivated B cells (NF-κB) in mice
@ast
The G-protein-coupled bile aci ...... ivated B cells (NF-κB) in mice
@en
type
label
The G-protein-coupled bile aci ...... ivated B cells (NF-κB) in mice
@ast
The G-protein-coupled bile aci ...... ivated B cells (NF-κB) in mice
@en
prefLabel
The G-protein-coupled bile aci ...... ivated B cells (NF-κB) in mice
@ast
The G-protein-coupled bile aci ...... ivated B cells (NF-κB) in mice
@en
P2093
P2860
P921
P356
P1433
P1476
The G-protein-coupled bile aci ...... ivated B cells (NF-κB) in mice
@en
P2093
Barry M Forman
Wei-Dong Chen
Wendong Huang
Yan-Dong Wang
P2860
P304
P356
10.1002/HEP.24525
P407
P577
2011-08-11T00:00:00Z