TGR5 potentiates GLP-1 secretion in response to anionic exchange resins. - Wikidata - awgldk - TriplyDB

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

http://www.wikidata.org/entity/Q35996467

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Recent advances in understanding and managing cholestasis Stimulation of incretin secreting cells Bile acids, obesity, and the metabolic syndrome Bile acids as metabolic regulators Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells Identification of miR-26a as a target gene of bile acid receptor GPBAR-1/TGR5 Identification of key amino acid residues in the hTGR5-nomilin interaction and construction of its binding model.Lowering low-density lipoprotein cholesterol levels in patients with type 2 diabetes mellitus.PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis.Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer.Vegetarian diets and glycemic control in diabetes: a systematic review and meta-analysis.TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation Intestinal transport and metabolism of bile acids Unraveling the environmental and genetic interactions in atherosclerosis: Central role of the gut microbiota.Specific inhibition of bile acid transport alters plasma lipids and GLP-1 Implications of microbiota and bile acid in liver injury and regeneration.The gut microbiota and metabolic disease: current understanding and future perspectives.Activation of bile acid signaling improves metabolic phenotypes in high-fat diet-induced obese mice Importance of Large Intestine in Regulating Bile Acids and Glucagon-Like Peptide-1 in Germ-Free Mice.Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids.Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice.Pleiotropic roles of bile acids in metabolism.Systemic bile acid sensing by G protein-coupled bile acid receptor 1 (GPBAR1) promotes PYY and GLP-1 release.Intestinally-targeted TGR5 agonists equipped with quaternary ammonium have an improved hypoglycemic effect and reduced gallbladder filling effect.Elevated First-Trimester Total Bile Acid is Associated with the Risk of Subsequent Gestational Diabetes.OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition.Potential mediators linking gut bacteria to metabolic health: a critical view.GPBA: a GPCR for bile acids and an emerging therapeutic target for disorders of digestion and sensation.Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a CYP7A1-AKT-mTOR Axis in Mice.The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders.Bile acid receptors as targets for drug development.Vitamin D and energy homeostasis: of mice and men.The bile acid TGR5 membrane receptor: from basic research to clinical application.Neuro-humoral signalling by bile acids and the TGR5 receptor in the gastrointestinal tract.Bile acid sequestrants: glucose-lowering mechanisms and efficacy in type 2 diabetes.TGR5 in inflammation and cardiovascular disease.Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon.Subchronic treatment with grape-seed phenolics inhibits ghrelin production despite a short-term stimulation of ghrelin secretion produced by bitter-sensing flavanols.TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro.

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P2860

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

http://www.wikidata.org/entity/Q35996467

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

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TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

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type

label

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

@ast

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

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prefLabel

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

@ast

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

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Scientific Reports

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TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.

@en

P2093

Adriano Maida

http://www.w3.org/2001/XMLSchema#string

Mitsuhiro Watanabe

http://www.w3.org/2001/XMLSchema#string

Mitsunori Nomura

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Taoufiq Harach

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Thijs W H Pols

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P2860

Proglucagon gene expression is induced by gastrin-releasing peptide in a mouse enteroendocrine cell line

Identification of membrane-type receptor for bile acids (M-BAR)

A G protein-coupled receptor responsive to bile acids

A simple method for the isolation and purification of total lipides from animal tissues

Colesevelam HCl improves glycemic control and reduces LDL cholesterol in patients with inadequately controlled type 2 diabetes on sulfonylurea-based therapy

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

The Physiology of Glucagon-like Peptide 1

Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man

Proglucagon gene expression is regulated by a cyclic AMP-dependent pathway in rat intestine.

TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading.

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430

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10.1038/SREP00430

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2

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Kristina Schoonjans

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2012-05-30T00:00:00Z

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225184822

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1050537609

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22666533

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3362799

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