Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag
about
Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tagClick chemistry in complex mixtures: bioorthogonal bioconjugationGlycotherapy: new advances inspire a reemergence of glycans in medicineDevelopment and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal ReactionA genetically encoded aldehyde for rapid protein labellingSynthesis of an Aminooxy Derivative of the Trisaccharide Globotriose Gb3Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2011-2012.Emerging technologies for making glycan-defined glycoproteinsA PEGylated photocleavable auxiliary mediates the sequential enzymatic glycosylation and native chemical ligation of peptides.A latent reactive handle for functionalising heparin-like and LMWH deca- and dodecasaccharides.Site-specific chemical protein conjugation using genetically encoded aldehyde tagsFormylbenzene diazonium hexafluorophosphate reagent for tyrosine-selective modification of proteins and the introduction of a bioorthogonal aldehyde.A Pictet-Spengler ligation for protein chemical modificationTetrasaccharide iteration synthesis of a heparin-like dodecasaccharide and radiolabelling for in vivo tissue distribution studies.Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion.Chemical and chemoenzymatic synthesis of glycoproteins for deciphering functions.Synthesis of the tumor associative α-aminooxy disaccharide of the TF antigen and its conjugation to a polysaccharide immune stimulant.Resolving the α-glycosidic linkage of arginine-rhamnosylated translation elongation factor P triggers generation of the first ArgRha specific antibody.Synthesis of post-translationally modified proteins.Multivalent glyco(cyclo)peptides.Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.Multivalent presentation of carbohydrates by 3(14)-helical peptide templates: synthesis, conformational analysis using CD spectroscopy and saccharide recognition.Recent Developments in Synthetic Carbohydrate-Based Diagnostics, Vaccines, and Therapeutics.Enterocyte glycosylation is responsive to changes in extracellular conditions: implications for membrane functions.Site-selective incorporation and ligation of protein aldehydes.N-O linkage in carbohydrates and glycoconjugates.Probing the influence of protecting groups on the anomeric equilibrium in sialic acid glycosides with the persistent radical effectChemoenzymatic Fc glycosylation via engineered aldehyde tags.Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates.Synthetically defined glycoprotein vaccines: current status and future directions.Bifunctional dendrons for multiple carbohydrate presentation via carbonyl chemistry.Piperidine-based glycodendrons as protein N-glycan prosthetics.Mutation of Conserved Residues Increases in Vitro Activity of the Formylglycine-Generating Enzyme.Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycine-Generating Enzyme.One-Step Derivatization of Reducing Oligosaccharides for Rapid and Live-Cell-Compatible Chelation-Assisted CuAAC Conjugation.Synthesis of and specific antibody generation for glycopeptides with arginine N-GlcNAcylation.
P2860
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P2860
Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Protein glycoengineering enabl ...... netically encoded aldehyde tag
@ast
Protein glycoengineering enabl ...... netically encoded aldehyde tag
@en
type
label
Protein glycoengineering enabl ...... netically encoded aldehyde tag
@ast
Protein glycoengineering enabl ...... netically encoded aldehyde tag
@en
prefLabel
Protein glycoengineering enabl ...... netically encoded aldehyde tag
@ast
Protein glycoengineering enabl ...... netically encoded aldehyde tag
@en
P2093
P2860
P356
P1476
Protein glycoengineering enabl ...... netically encoded aldehyde tag
@en
P2093
Carolyn R Bertozzi
Helen H Yu
Jason E Hudak
P2860
P304
16127-16135
P356
10.1021/JA206023E
P407
P577
2011-09-14T00:00:00Z