Structure-function map of the receptor site for β-scorpion toxins in domain II of voltage-gated sodium channels
about
Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( -TRTX-Hh2a)Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of Escherichia coliA distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1aProton-dependent inhibition of the cardiac sodium channel Nav1.5 by ranolazineStructure and function of voltage-gated sodium channels at atomic resolution.Modular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels.Insect-Active Toxins with Promiscuous Pharmacology from the African Theraphosid Spider Monocentropus balfouriSynthesis and analgesic effects of μ-TRTX-Hhn1b on models of inflammatory and neuropathic pain.Voltage-gated sodium channels at 60: structure, function and pathophysiology.A surface plasmon resonance approach to monitor toxin interactions with an isolated voltage-gated sodium channel paddle motif.Binding modes of μ-conotoxin to the bacterial sodium channel (NaVAb)Allosteric interactions between receptor site 3 and 4 of voltage-gated sodium channels: a novel perspective for the underlying mechanism of scorpion sting-induced pain.Mapping the interaction site for a β-scorpion toxin in the pore module of domain III of voltage-gated Na(+) channelsStructural Insights into the Atomistic Mechanisms of Action of Small Molecule Inhibitors Targeting the KCa3.1 Channel Pore.Finding Channels.Opening the shaker K+ channel with hanatoxin.Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana.Computational methods of studying the binding of toxins from venomous animals to biological ion channels: theory and applications.Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET.Advances in targeting voltage-gated sodium channels with small molecules.Multiscale Modeling in the Clinic: Drug Design and DevelopmentActivation of sodium channels by α-scorpion toxin, BmK NT1, produced neurotoxicity in cerebellar granule cells: an association with intracellular Ca2+ overloading.Computational Models for Predictive Cardiac Ion Channel Pharmacology.Total chemical synthesis of biologically active fluorescent dye-labeled Ts1 toxinScorpion β-toxin interference with NaV channel voltage sensor gives rise to excitatory and depressant modes.Nav channel binder containing a specific conjugation-site based on a low toxicity β-scorpion toxin.Structural Models of Ligand-Bound Sodium Channels.Investigation of Binding Modes and Functional Surface of Scorpion Toxins ANEP to Sodium Channels 1.7.Sodium channels and pain: from toxins to therapies.Selective Closed-State Nav1.7 Blocker JZTX-34 Exhibits Analgesic Effects against Pain.Subtype Specificity of β-Toxin Tf1a from in Voltage Gated Sodium ChannelsPredicting Structural Details of the Sodium Channel Pore Basing on Animal Toxin Studies
P2860
Q27678595-46B0CDAC-AC83-4834-969A-9A756C847D5CQ27679850-21608EA4-4351-4FCF-8CA8-D09EA6BB4A39Q27684660-0AB466CB-F855-4688-BF3D-50A14FD3E825Q28293492-B8A74DDA-FF76-424E-B32E-629A804579BFQ29030031-F03C23FF-3599-4007-8DB5-C6868307B077Q30430009-9B38BE38-9C1A-47E2-8588-75EDA5EB9023Q33744738-49057D5F-61DC-49CA-9E4F-A10FB4B39C9FQ34101792-6D09D234-7819-4874-A4DA-8FF75CFE1403Q34265707-71D27E4B-88E4-49E7-AA7A-AF0AD0089E45Q35014380-C4D7ABD1-F35E-4D4B-B31C-C5132767B269Q35743263-99A236F8-ECD1-45BF-98EE-18C358D39DB4Q36181590-0BD6E7DA-6EA3-4B78-94B5-462AA9BE4EE7Q36216475-03B83A9D-D3F0-46A7-8EFB-4FA0B45FECEBQ36261948-10EF08BA-6C7C-4BE1-81CD-236334C13380Q36301315-63D45CC6-913C-43CC-B76D-34912B1B8695Q36568507-2601936F-3E2E-46E1-B0AB-6F8AF48DC3F1Q37012447-D53262F8-B16D-44C1-B780-7B4AC418CB23Q37158502-B3ACDFE5-8AA5-45BB-A6A0-4A9834696C37Q37695974-C6B0BE9E-635A-4274-8DD6-D3066E7BE188Q38040330-169AF779-0D96-4CD4-9848-522FAE856EC6Q38736948-A72D3070-46F9-4E95-B1DD-1BD14ABF8A5CQ39672702-84469E6F-1E4D-4CFD-AB14-A266911FA1A3Q40243231-F4CB0C5D-3A5D-4F91-A626-1F3BCA1BB81EQ41091685-B5CC078E-D586-4AC6-B2A8-B8C606EB4AD6Q42562889-9311760A-8151-4B29-B1D4-2FCDAC77C63CQ46318691-735378A0-5355-4801-A2EE-16F29BB2CA31Q47236925-BC381525-249D-4DEE-9285-1E6DCC761D10Q47397997-6F25AB2E-56E6-43A6-AE17-68CFFC559837Q48337085-D0445BB7-749F-4768-B1A8-45862CA572E1Q49375959-19941C97-5510-4845-84E0-6685CA82B311Q58717599-2D83A907-44C3-4B45-B69D-8E6CC6728D5FQ58797314-908B017C-B65E-461E-979B-20C42800D90D
P2860
Structure-function map of the receptor site for β-scorpion toxins in domain II of voltage-gated sodium channels
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structure-function map of the ...... voltage-gated sodium channels
@ast
Structure-function map of the ...... voltage-gated sodium channels
@en
type
label
Structure-function map of the ...... voltage-gated sodium channels
@ast
Structure-function map of the ...... voltage-gated sodium channels
@en
prefLabel
Structure-function map of the ...... voltage-gated sodium channels
@ast
Structure-function map of the ...... voltage-gated sodium channels
@en
P2093
P2860
P356
P1476
Structure-function map of the ...... voltage-gated sodium channels
@en
P2093
Dalia Gordon
Izhar Karbat
Joel Z Zhang
Lior Cohen
Michael Gurevitz
Todd Scheuer
William A Catterall
P2860
P304
33641-33651
P356
10.1074/JBC.M111.282509
P407
P577
2011-07-27T00:00:00Z