Ca2+-binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in Ca2+-dependent activation.
about
Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolutionGating mechanism of BK (Slo1) channels: so near, yet so farThe RCK1 high-affinity Ca2+ sensor confers carbon monoxide sensitivity to Slo1 BK channelsRegulation of bestrophin Cl channels by calcium: role of the C terminusThe RCK2 domain of the human BKCa channel is a calcium sensorBeta1 subunits facilitate gating of BK channels by acting through the Ca2+, but not the Mg2+, activating mechanismsStructural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channelBK channels: multiple sensors, one activation gateNew disguises for an old channel: MaxiK channel beta-subunitsA BK (Slo1) channel journey from molecule to physiology.Cysteine residue 911 in C-terminal tail of human BK(Ca)α channel subunit is crucial for its activation by carbon monoxide.The RCK1 domain of the human BKCa channel transduces Ca2+ binding into structural rearrangementsStepwise contribution of each subunit to the cooperative activation of BK channels by Ca2+.Ca(2+) influx and opening of Ca(2+)-activated K(+) channels in muscle fibers from control and mdx mice.Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BK(Ca) channelVoltage-dependent conformational changes in human Ca(2+)- and voltage-activated K(+) channel, revealed by voltage-clamp fluorometry.Sodium (2-sulfonatoethyl) methanethiosulfonate prevents S-nitroso-L-cysteine activation of Ca2+-activated K+ (BKCa) channels in myocytes of the guinea-pig taenia caecaMetal-driven operation of the human large-conductance voltage- and Ca2+-dependent potassium channel (BK) gating ring apparatus.Allosteric modulation of ion channels: the case of maxi-K.Two helices in the third intracellular loop determine anoctamin 1 (TMEM16A) activation by calciumThe contribution of RCK domains to human BK channel allosteric activationBarium ions selectively activate BK channels via the Ca2+-bowl siteInteraction of the BKCa channel gating ring with dendrotoxins.Relative transmembrane segment rearrangements during BK channel activation resolved by structurally assigned fluorophore-quencher pairing.Effects of multiple metal binding sites on calcium and magnesium-dependent activation of BK channelsIntra- and intersubunit cooperativity in activation of BK channels by Ca2+A tail of multiple calcium-sensing domainsMechanisms of two modulatory actions of the channel-binding protein Slob on the Drosophila Slowpoke calcium-dependent potassium channelA role for the S0 transmembrane segment in voltage-dependent gating of BK channels.Modulation of the conductance-voltage relationship of the BK Ca channel by mutations at the putative flexible interface between two RCK domains.On the conformation of the COOH-terminal domain of the large mechanosensitive channel MscL.Gating and conductance properties of BK channels are modulated by the S9-S10 tail domain of the alpha subunit. A study of mSlo1 and mSlo3 wild-type and chimeric channels.Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channelsAllosteric regulation of BK channel gating by Ca(2+) and Mg(2+) through a nonselective, low affinity divalent cation siteIntracellular Mg(2+) enhances the function of BK-type Ca(2+)-activated K(+) channels.Divalent cation sensitivity of BK channel activation supports the existence of three distinct binding sites.The amino terminus of Slob, Slowpoke channel binding protein, critically influences its modulation of the channel.Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity.Mapping the BKCa channel's "Ca2+ bowl": side-chains essential for Ca2+ sensing.The NH2 terminus of RCK1 domain regulates Ca2+-dependent BK(Ca) channel gating.
P2860
Q24595712-ACBA6854-DC61-4E7A-A50C-DBB511E08D20Q24644547-B4AF0D92-AC09-4482-A0A3-58F98884E094Q24652302-D35DCEF7-89B2-4368-808F-D06A02C5A57CQ24655410-16B279D3-4516-46A2-BF6B-4A48E78C35FDQ24657358-B2F51D8C-7FB7-4E90-888F-67D5C3EC9FE3Q24681158-7517E28E-127F-4EFB-872B-8E47E32C8C2EQ24684666-27FA5E32-9FF0-44DA-A94C-4BD129122201Q26830341-206CF4DC-1064-4A3D-838D-CB8A4D755A80Q28215718-1C69C662-1A6E-462A-AEC5-413D08103EB7Q33702537-55D7A1DB-89C4-438C-9050-96FBD0D96D3CQ33814349-13814475-DD8B-4473-B3F5-112AFDE14695Q34028265-55233168-41B5-46E3-B0E6-D26680D3E841Q34038735-94A55E13-39F6-4CC5-A66A-F28511BD102FQ34178063-4089E6F3-9E3E-4EB8-B579-CE0463FDFB54Q34368477-B06BDA18-9330-4759-88D1-E3C9B2E26119Q35033825-7E7F347A-7DC1-47AD-A630-0D364045ADE0Q35045523-BD36B13C-5D00-4148-AD6A-6FA5E9BDEB1DQ35063533-4F28A2C7-7205-46EF-A0CF-D31352B2B34DQ35740015-7F1DD243-64BC-4097-8FEE-C3D630029149Q35851705-9E096001-066B-4987-B570-B860D1742305Q36052381-C4B56C94-B6CB-4C3A-B61E-6F3AE133B1FCQ36094231-06CB58A3-E124-41F9-97A5-1F6ABDCEFDC7Q36125024-DBD8ADD4-C753-4755-9DB9-6E50F34E81DAQ36130322-9F917D18-27F9-46BD-8D84-9888CE73FC16Q36295550-EC5F0BA4-572B-4CBD-A66D-201248C3F470Q36295837-292A0F6C-B144-4066-B8E6-C45606E143D9Q36295850-BCA44DDF-782F-4E7B-B4A0-A6ED70FA04E1Q36295869-A4F3BE46-7D71-40AD-8510-0D93AE6E4F11Q36295991-52F6BAEA-B271-4243-970F-C60CFF5179B2Q36303199-1110A095-A487-44A6-B955-5D5468960788Q36412392-B1D68894-6156-4751-AF25-D162E3F6F21BQ36436409-21F715F4-7B6B-477E-B422-62322080ECE0Q36436593-BFC9A25F-32B7-4D01-B14D-2C82F1E27A26Q36445217-DA2A3E00-021B-4D64-8C1C-6323992455FFQ36445229-E821A9FE-3089-495F-B3A8-3FE172654CCBQ36445694-9F5207A9-4C6C-47FC-BBD1-4B60D1BF08E7Q36445993-2884D0D6-5C02-4D97-A060-06F502070D09Q36447158-5F0EC5FA-76B7-4132-86A5-B51F3EDF11AEQ36447234-4819B89C-60AA-4CF5-8CDE-F43D29292A7AQ36493518-54BF992C-3688-42F6-88CB-FDC83B1F8106
P2860
Ca2+-binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in Ca2+-dependent activation.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Ca2+-binding activity of a COO ...... in Ca2+-dependent activation.
@ast
Ca2+-binding activity of a COO ...... in Ca2+-dependent activation.
@en
type
label
Ca2+-binding activity of a COO ...... in Ca2+-dependent activation.
@ast
Ca2+-binding activity of a COO ...... in Ca2+-dependent activation.
@en
prefLabel
Ca2+-binding activity of a COO ...... in Ca2+-dependent activation.
@ast
Ca2+-binding activity of a COO ...... in Ca2+-dependent activation.
@en
P2093
P2860
P356
P1476
Ca2+-binding activity of a COO ...... in Ca2+-dependent activation.
@en
P2093
P2860
P304
P356
10.1073/PNAS.081072398
P407
P577
2001-03-27T00:00:00Z