The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes.
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Interleukin-6 induces hepcidin expression through STAT3Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overloadBone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in miceSoluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR sitePathophysiology of hereditary hemochromatosisSLC40A1 Q248H allele frequencies and Q248H-associated risk of non-HFE iron overload in persons of sub-Saharan African descentHepcidin and Host Defense against Infectious Diseases.Hepcidin: regulation of the master iron regulatorAnemia in inflammatory bowel disease: an under-estimated problem?Hepcidin expression in the liver: relatively low level in patients with chronic hepatitis CDistinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortusDorsomorphin inhibits BMP signals required for embryogenesis and iron metabolismThe role of iron in brain ageing and neurodegenerative disorders.High-throughput matrix-assisted laser desorption ionization-time-of-flight mass spectrometry method for quantification of hepcidin in human urineHepcidin expression by human monocytes in response to adhesion and pro-inflammatory cytokines.Thioesterase superfamily member 2 (Them2) and phosphatidylcholine transfer protein (PC-TP) interact to promote fatty acid oxidation and control glucose utilization.Regulation of hepcidin transcription by interleukin-1 and interleukin-6.The role of iron in the immune response to bacterial infectionFerroportin disease: a systematic meta-analysis of clinical and molecular findings.Hepcidin regulation by BMP signaling in macrophages is lipopolysaccharide dependent.Normal iron metabolism and the pathophysiology of iron overload disordersNew insights into the regulation of iron homeostasis.Iron and inflammation - the gut reaction.Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation.Iron homeostasis and the inflammatory responseHighly Elevated Serum Hepcidin in Patients with Acute Myeloid Leukemia prior to and after Allogeneic Hematopoietic Cell Transplantation: Does This Protect from Excessive Parenchymal Iron Loading?Iron and immunity: immunological consequences of iron deficiency and overload.5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated prFirst phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin.Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice.Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.The emerging role of the liver in iron metabolism.Iron storage disease: facts, fiction and progress.Impaired hepcidin expression in alpha-1-antitrypsin deficiency associated with iron overload and progressive liver disease.Mechanisms of disease: The role of hepcidin in iron homeostasis--implications for hemochromatosis and other disorders.Tumour necrosis factor alpha downregulates human hemojuvelin expression via a novel response element within its promoter.Molecular insights into the pathogenesis of hereditary haemochromatosisHydrogen Sulfide Attenuates Inflammatory Hepcidin by Reducing IL-6 Secretion and Promoting SIRT1-Mediated STAT3 Deacetylation.Hematological alterations in diabetic rats - Role of adipocytokines and effect of citrus flavonoids
P2860
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P2860
The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The IL-6- and lipopolysacchari ...... lobulin-deficient hepatocytes.
@ast
The IL-6- and lipopolysacchari ...... lobulin-deficient hepatocytes.
@en
type
label
The IL-6- and lipopolysacchari ...... lobulin-deficient hepatocytes.
@ast
The IL-6- and lipopolysacchari ...... lobulin-deficient hepatocytes.
@en
prefLabel
The IL-6- and lipopolysacchari ...... lobulin-deficient hepatocytes.
@ast
The IL-6- and lipopolysacchari ...... lobulin-deficient hepatocytes.
@en
P2093
P2860
P356
P1476
The IL-6- and lipopolysacchari ...... lobulin-deficient hepatocytes.
@en
P2093
Ernest Beutler
Hongfan Peng
Pauline Lee
Terri Gelbart
P2860
P304
P356
10.1073/PNAS.0403108101
P407
P577
2004-06-10T00:00:00Z