TP53 tumor suppressor gene: a model for investigating human mutagenesis.
about
Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parametersAflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytesComputational approaches for predicting the biological effect of p53 missense mutations: a comparison of three sequence analysis based methodsProperties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens.The transforming and suppressor functions of p53 alleles: effects of mutations that disrupt phosphorylation, oligomerization and nuclear translocation.Germline p53 mutations are frequently detected in young children with rhabdomyosarcoma.Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors.ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia.Role of nitric oxide in tumour progression with special reference to a murine breast cancer model.The significance of immunohistochemistry in the diagnosis and therapy of neoplasms.p53-mediated cellular response to DNA damage in cells with replicative hepatitis B virusPrioritization of candidate disease genes by topological similarity between disease and protein diffusion profiles.New insights into p53 activationDatabase of p53 gene somatic mutations in human tumors and cell lines.Genetic alterations associated with adult diffuse astrocytic tumors.The role of the cellular antioxidant defense in oxidant carcinogenesis.Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides.Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient miceConfiguration of the TP53 gene as an independent prognostic parameter of myelodysplastic syndrome.Oncogenes in melanomas.Leukemia in Down syndrome: a review.The polymerase chain reaction: its use in the molecular characterization and diagnosis of cancers.Cancer risks from germline p53 mutations.Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome.Molecular Markers with Predictive and Prognostic Relevance in Lung CancerConformational effects of environmentally induced, cancer-related mutations in the p53 protein.Heterogeneity in intratumor distribution of p53 mutations in human prostate cancerMutational spectrum of the p53 gene in human small-cell lung cancer and relationship to clinicopathological data.Immunohistochemical study of p53 in human lung carcinomas.Chromosome 17 abnormalities and TP53 mutations in adult soft tissue sarcomas.Chromosomal aberrations in soft tissue tumors. Relevance to diagnosis, classification, and molecular mechanisms.Gain-of-function mutations of the p53 gene induce lymphohematopoietic metastatic potential and tissue invasiveness.Molecular aspects of esophageal squamous cell carcinoma carcinogenesis.Comparative genomic hybridization identifies loss of 18q22-qter as an early and specific event in tumorigenesis of midgut carcinoidsFunctional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations.Prognostic significance of TP53 alterations in breast carcinoma.p53 protein overexpression identifies a group of central primitive neuroectodermal tumours with poor prognosis.p53 mutations in cervical carcinogenesis--low frequency and lack of correlation with human papillomavirus statusAnalyses of p53 antibodies in sera of patients with lung carcinoma define immunodominant regions in the p53 protein.p53 immunohistochemical analysis in breast cancer with four monoclonal antibodies: comparison of staining and PCR-SSCP results.
P2860
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P2860
TP53 tumor suppressor gene: a model for investigating human mutagenesis.
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
TP53 tumor suppressor gene: a model for investigating human mutagenesis.
@ast
TP53 tumor suppressor gene: a model for investigating human mutagenesis.
@en
type
label
TP53 tumor suppressor gene: a model for investigating human mutagenesis.
@ast
TP53 tumor suppressor gene: a model for investigating human mutagenesis.
@en
prefLabel
TP53 tumor suppressor gene: a model for investigating human mutagenesis.
@ast
TP53 tumor suppressor gene: a model for investigating human mutagenesis.
@en
P356
P1476
TP53 tumor suppressor gene: a model for investigating human mutagenesis.
@en
P2093
Caron de Fromentel C
P356
10.1002/GCC.2870040102
P577
1992-01-01T00:00:00Z