A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.
about
The expanding regulatory universe of p53 in gastrointestinal cancerDysregulation of microRNA biogenesis in cancer: the impact of mutant p53 on Drosha complex activityRegulation of Mutant p53 Protein ExpressionmiR-135a inhibits tumor metastasis and angiogenesis by targeting FAK pathwayImproved low-rank matrix recovery method for predicting miRNA-disease association.Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion.Selective targeting of KRAS-mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-mutant cellsmicroRNAs: short non-coding bullets of gain of function mutant p53 proteins.The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiationRBMMMDA: predicting multiple types of disease-microRNA associations.Growth differentiation factor-15 encodes a novel microRNA 3189 that functions as a potent regulator of cell death.Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processingHIV-1 Infection-Induced Suppression of the Let-7i/IL-2 Axis Contributes to CD4(+) T Cell Death.Understanding the CREB1-miRNA feedback loop in human malignancies.An integrative transcriptomic analysis reveals p53 regulated miRNA, mRNA, and lncRNA networks in nasopharyngeal carcinoma.Targeting mutant p53 in cancer: a long road to precision therapy.A regulatory BMI1/let-7i/ERK3 pathway controls the motility of head and neck cancer cellsPRIMA-1 induces p53-mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation.p53 shades of Hippo.Li-Fraumeni Syndrome Disease Model: A Platform to Develop Precision Cancer Therapy Targeting Oncogenic p53.Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.MicroRNA therapy inhibits hepatoblastoma growth in vivo by targeting β-catenin and Wnt signaling.A step-by-step microRNA guide to cancer development and metastasis.Abrogating the interplay between IGF2BP1, 2 and 3 and IGF1R by let-7i arrests hepatocellular carcinoma growth.MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus.Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.
P2860
Q26742058-1CA97375-1E6D-444F-AAF0-6EBD3246FEAFQ26766173-37B1E4D4-481C-4667-AF2E-4797FF5A37A0Q26770579-9B8FF49C-1214-481B-94D9-0B886B660C6CQ33761677-8DCF6308-4B7E-4CDC-B72F-142A88FB9E11Q33920938-CE6C04BE-9B18-49EC-AC51-71462D82D9A5Q34028555-5EB0387E-A48D-4B8A-BF2F-C2C9E1ABA112Q34365804-0A9A6A42-4708-46B4-90E0-2EA2CABFF1CFQ34832663-AEABDE82-00E2-4B1F-A0F5-F5817BF7556BQ35280248-10CD1828-705E-430F-A93B-1420BAF48FE7Q36034189-EA9C0E31-F723-488A-97A2-643FF685C2C5Q36040617-C02A199E-21C8-4E39-AFB7-4E2EC9E423CDQ36056465-8D6A832E-C6FE-4F18-8466-A5D8A5E226C9Q36689074-153880B6-B65A-4C67-8BF5-4D4289858C4CQ36870934-785F26C8-AC0C-49F8-A552-88496AF37772Q38802458-2A671E88-5FDB-4BD0-8F4B-EAB83D0A527AQ38828239-2ABDC8AE-F0CD-4D53-B578-BCD785D49797Q38997351-A4294AAC-79D8-4C52-8D9A-1476BB9BFE9CQ42244159-F6A98D9E-0F60-40D0-ACAD-524B77134FFFQ47371251-F95CC687-59CA-4C88-A08F-9982D1485183Q47850800-C906E8D3-1263-4592-9817-CCB3D6BBA589Q48690318-16532591-4BF7-4E63-AA84-3CB30B48BBEFQ51679220-4DA9ACE4-E013-4EAF-8E08-CB642D716E01Q51742707-6F44766F-08B6-4A37-98CC-E1187A88E3CBQ52562647-3674C171-9B75-4481-AECC-5AFE6BBC7BBFQ53764455-1BDBB3AB-4968-4E43-B69B-87B04421A144Q55021852-55E0C756-5C21-45FB-AC9F-85F84197B622Q55026448-385CCCB6-25B6-4ABD-B9B8-2AE15157BFD1
P2860
A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A mutant p53/let-7i-axis-regul ...... tion, invasion and metastasis.
@ast
A mutant p53/let-7i-axis-regul ...... tion, invasion and metastasis.
@en
type
label
A mutant p53/let-7i-axis-regul ...... tion, invasion and metastasis.
@ast
A mutant p53/let-7i-axis-regul ...... tion, invasion and metastasis.
@en
prefLabel
A mutant p53/let-7i-axis-regul ...... tion, invasion and metastasis.
@ast
A mutant p53/let-7i-axis-regul ...... tion, invasion and metastasis.
@en
P2093
P2860
P50
P356
P1433
P1476
A mutant p53/let-7i-axis-regul ...... ation, invasion and metastasis
@en
P2093
L A Martinez
L Varanasi
M Subramanian
P S Meltzer
P2860
P2888
P304
P356
10.1038/ONC.2014.46
P407
P577
2014-03-24T00:00:00Z