Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
about
Inhibited intercellular communication as a mechanistic link between teratogenesis and carcinogenesisElevated sister chromatid exchange phenotype of Bloom syndrome cells is complemented by human chromosome 15Evidence for increased in vivo mutation and somatic recombination in Bloom's syndromeIncreased rate of spontaneous mitotic recombination in T lymphocytes from a Bloom's syndrome patient using a flow-cytometric assay at HLA-A locusStage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome geneMutation of the murine Bloom's syndrome gene produces global genome destabilizationImmunological lesions in human uracil DNA glycosylase: association with Bloom syndrome.Joining of linear plasmid DNA is reduced and error-prone in Bloom's syndrome cells.Molecular evidence that homologous recombination occurs in proliferating human somatic cells.High frequency of large spontaneous deletions of DNA in tumor-derived CHEF cells"Bad Luck Mutations": DNA Mutations Are not the Whole Answer to Understanding Cancer Risk.Structural alterations of DNA ligase I in Bloom syndromeMouse models of inherited cancer syndromesDrug-susceptible Mycobacterium tuberculosis Beijing genotype does not develop mutation-conferred resistance to rifampin at an elevated rateDNA ligase III is the major high molecular weight DNA joining activity in SV40-transformed human fibroblasts: normal levels of DNA ligase III activity in Bloom syndrome cellsProfile of Stephen T. WarrenBloom syndrome: a single complementation group defines patients of diverse ethnic origin.Loss of the bloom syndrome helicase increases DNA ligase 4-independent genome rearrangements and tumorigenesis in aging Drosophila."...Rewritten in the skin": clues to skin biology and aging from inherited disease.Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells.Altered temporal expression of DNA repair in hypermutable Bloom's syndrome cells12-O-tetradecanoylphorbol 13-acetate-inducible proteins are synthesized at an increased rate in Bloom syndrome fibroblasts.A subgroup of microsatellite stable colorectal cancers has elevated mutation rates and different responses to alkylating and oxidising agents.Spontaneous rearrangement of integrated simian virus 40 DNA in nine transformed rodent cell lines.Evolution of Microbial Quorum Sensing to Human Global Quorum Sensing: An Insight into How Gap Junctional Intercellular Communication Might Be Linked to the Global Metabolic Disease Crisis.Assessing the value of autologous and allogeneic cells for regenerative medicine.Repair of DNA damage induced by reactive oxygen species.Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome.Spontaneous mutation rate in retinoblastomaBromodeoxyuridine does not contribute to sister chromatid exchange events in normal or Bloom syndrome cells.Somatic intragenic recombination within the mutated locus BLM can correct the high sister-chromatid exchange phenotype of Bloom syndrome cells.What roles do colon stem cells and gap junctions play in the left and right location of origin of colorectal cancers?Rapid fluorometric detection of drug resistant tumour cells.Growth defect and mutator phenotypes of RecQ-deficient Neurospora crassa mutants separately result from homologous recombination and nonhomologous end joining during repair of DNA double-strand breaks.Low-sister-chromatid-exchange Bloom syndrome cell lines: an important new tool for mapping the basic genetic defect in Bloom syndrome and for unraveling the biology of human tumor development.Transition of phenotypic dimorphism with regard to spontaneous sister chromatid exchange in Epstein-Barr virus-transformed Bloom's syndrome lymphoblastoid cell lines.Two types of DNA ligase I activity in lymphoblastoid cells from patients with Bloom's syndrome.
P2860
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P2860
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
description
1981 nî lūn-bûn
@nan
1981 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1981 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
name
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
@ast
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
@en
type
label
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
@ast
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
@en
prefLabel
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
@ast
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
@en
P2093
P2860
P356
P1476
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
@en
P2093
P2860
P304
P356
10.1073/PNAS.78.5.3133
P407
P577
1981-05-01T00:00:00Z