Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes. - Wikidata - awgldk - TriplyDB

Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes.

Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes.

http://www.wikidata.org/entity/Q35405076

about

Th17 Cells in Type 1 Diabetes: Role in the Pathogenesis and Regulation by Gut Microbiome Concise Review: Cell-Based Therapies and Other Non-Traditional Approaches for Type 1 Diabetes Antigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune Diseases ISA-2011B, a Phosphatidylinositol 4-Phosphate 5-Kinase α Inhibitor, Impairs CD28-Dependent Costimulatory and Pro-inflammatory Signals in Human T Lymphocytes.Aberrant muscle antigen exposure in mice is sufficient to cause myositis in a Treg cell-deficient milieu Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes.Foxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals.Th1/Th17 plasticity is a marker of advanced β cell autoimmunity and impaired glucose tolerance in humans The changing landscape of type 1 diabetes: recent developments and future frontiers.Follicular helper T cell signature in type 1 diabetes PTPN2 controls differentiation of CD4⁺ T cells and limits intestinal inflammation and intestinal dysbiosis.Role of the gastrointestinal ecosystem in the development of type 1 diabetes.Immunological Basis for Rapid Progression of Diabetes in Older NOD Mouse Recipients Post BM-HSC Transplantation Rapamycin ameliorates experimental autoimmune uveoretinitis by inhibiting Th1/Th2/Th17 cells and upregulating CD4+CD25+ Foxp3 regulatory T cells.Follicular Helper T Cells in Autoimmunity.Expression of PD-1 Molecule on Regulatory T Lymphocytes in Patients with Insulin-Dependent Diabetes Mellitus.The Role of IL-17 and Th17 Lymphocytes in Autoimmune Diseases Can we vaccinate against Type 1 diabetes?Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues Regulatory properties of the intestinal microbiome effecting the development and treatment of diabetes A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment.The serum IL-6 profile and Treg/Th17 peripheral cell populations in patients with type 1 diabetes.Analyses of regulatory CD4+ CD25+ FOXP3+ T cells and observations from peripheral T cell subpopulation markers during the development of type 1 diabetes in children.Adaptive immunity, inflammation, and cardiovascular complications in type 1 and type 2 diabetes mellitus Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes.Shaping the (auto)immune response in the gut: the role of intestinal immune regulation in the prevention of type 1 diabetes.Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease.Cholinergic Stimulation Prevents the Development of Autoimmune Diabetes: Evidence for the Modulation of Th17 Effector Cells via an IFNγ-Dependent Mechanism.Islet antigen-specific Th17 cells can induce TNF-α-dependent autoimmune diabetes.Consumption of acidic water alters the gut microbiome and decreases the risk of diabetes in NOD mice.Interindividual variation in human T regulatory cells.TH17 Cells in Autoimmunity and Immunodeficiency: Protective or Pathogenic?Autologous regulatory T cells for the treatment of type 1 diabetes.The multiple origins of Type 1 diabetes.Cell-based interventions to halt autoimmunity in type 1 diabetes mellitus.Anti-cytokine therapies in T1D: Concepts and strategies.Forkhead box P3: the peacekeeper of the immune system.Immune modulation in humans: implications for type 1 diabetes mellitus.Alteration of regulatory T cells in type 1 diabetes mellitus: a comprehensive review.Rebamipide suppresses collagen-induced arthritis through reciprocal regulation of th17/treg cell differentiation and heme oxygenase 1 induction.

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Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes.

http://www.wikidata.org/entity/Q35405076

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Expansion of Th17 cells and fu ...... patients with type 1 diabetes.

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Expansion of Th17 cells and fu ...... patients with type 1 diabetes.

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Alessandra Ferraro

http://www.w3.org/2001/XMLSchema#string

Andrea Valle

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Angela Stabilini

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Antonio Secchi

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Carlo Socci

http://www.w3.org/2001/XMLSchema#string

Carlo Staudacher

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Paola Maffi

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Rita Nano

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Sven Olek

http://www.w3.org/2001/XMLSchema#string

P2860

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction.

Epigenetic control of the foxp3 locus in regulatory T cells

Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation.

Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects

Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes

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2903-2913

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10.2337/DB11-0090

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11

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60

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Lorenzo Piemonti

Manuela Battaglia

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2011-09-06T00:00:00Z

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51624243

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21896932

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type-1 diabetes

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3198077

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