about
Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathwayThe streetlight effect in type 1 diabetesRapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantationConcise Review: Cell-Based Therapies and Other Non-Traditional Approaches for Type 1 DiabetesAbnormalities of the Exocrine Pancreas in Type 1 DiabetesImmune Depletion in Combination with Allogeneic Islets Permanently Restores Tolerance to Self-Antigens in Diabetic NOD MiceCo-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice.Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplantThe role of interleukin 10 in the control of autoimmunity.Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.The puzzling world of murine T regulatory cells.Stability of human rapamycin-expanded CD4+CD25+ T regulatory cellsExpansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes.Combination of an Antigen-Specific Therapy and an Immunomodulatory Treatment to Simultaneous Block Recurrent Autoimmunity and Alloreactivity in Non-Obese Diabetic Mice.Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes.Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation.Tr1 cells: from discovery to their clinical application.Induction of transplantation tolerance via regulatory T cells.Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cellsReduction of circulating neutrophils precedes and accompanies type 1 diabetesRegulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.Autoimmune diabetic patients undergoing allogeneic islet transplantation: are we ready for a regulatory T-cell therapy?Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes.Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes.Roles of the protein tyrosine phosphatase PTPN22 in immunity and autoimmunity.Neutrophils and type 1 autoimmune diabetes.Experiments by nature: lessons on type 1 diabetes.Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications.Hurdles in therapy with regulatory T cells.Towards an Earlier and Timely Diagnosis of Type 1 Diabetes: Is it Time to Change Criteria to Define Disease Onset?IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo.STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.Lack of the protein tyrosine phosphatase PTPN22 strengthens transplant tolerance to pancreatic islets in mice.Heterogeneous CD3 expression levels in differing T cell subsets correlate with the in vivo anti-CD3-mediated T cell modulation.PTPN22 controls virally-induced autoimmune diabetes by modulating cytotoxic T lymphocyte responses in an epitope-specific manner.Calcineurin inhibitor-free immunosuppressive regimen in type 1 diabetes patients receiving islet transplantation: single-group phase 1/2 trial.WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells.Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner.
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description
hulumtuese
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onderzoeker
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researcher
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հետազոտող
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name
Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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Manuela Battaglia
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P106
P1153
7201908365
P21
P31
P496
0000-0003-4535-3152