Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models. - Wikidata - awgldk - TriplyDB

Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.

Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.

http://www.wikidata.org/entity/Q35415573

about

Pharmacokinetic application of a bio-analytical LC-MS method developed for 5-fluorouracil and methotrexate in mouse plasma, brain and urine.Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis.Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models.The effect of ABCG2 and ABCC4 on the pharmacokinetics of methotrexate in the brain.Pharmacogenetics and pharmacogenomics for rheumatoid arthritis responsiveness to methotrexate treatment: the 2013 update.Mrp2 is involved in the efflux and disposition of fosinopril.Restoring multidrug resistance-associated protein 3 attenuates cell proliferation in the polycystic kidney.

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P2860

Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.

http://www.wikidata.org/entity/Q35415573

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Dose-dependent disposition of ...... 3 gene knockout murine models.

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Drug Metabolism and Disposition

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Dose-dependent disposition of ...... 3 gene knockout murine models.

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Gary D Kruh

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James M Gallo

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Qingyu Zhou

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Zhan Wang

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P2860

Tissue distribution and induction of human multidrug resistant protein 3

Regulation of expression of the multidrug resistance-associated protein 2 (MRP2) and its role in drug disposition

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system.

Mammalian ABC transporters in health and disease.

Clinical pharmacokinetics of commonly used anticancer drugs.

Importance of P-glycoprotein for drug disposition in humans.

Oral methotrexate is as effective as intramuscular in maintenance therapy of acute lymphoblastic leukaemia.

The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability.

Silencing of genes by promoter hypermethylation: key event in rodent and human lung cancer.

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2155-2161

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10.1124/DMD.111.041228

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11

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39

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