Importance of P-glycoprotein for drug disposition in humans.
about
Drug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug deliveryA multi-system approach assessing the interaction of anticonvulsants with P-gpBiphasic regulation of P-glycoprotein function and expression by NO donors in Caco-2 cells.Combination analysis of NOS3, ABCB1 and IL23R polymorphisms with alcohol-induced osteonecrosis of the femoral head risk in Chinese malesBlood-brain barrier active efflux transporters: ATP-binding cassette gene family.Review article: prescribing medications in patients with cirrhosis - a practical guide.Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.Assessment of extracts from red yeast rice for herb-drug interaction by in-vitro and in-vivo assays.The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers.Vitreal kinetics of quinidine in rabbits in the presence of topically coadministered P-glycoprotein substrates/modulators.Mechanisms of the penetration of blood-borne substances into the brain.Nanostructured lipid carriers: versatile oral delivery vehicle.Organic cation transporters and their roles in antiretroviral drug disposition.ABC transporters in human lymphocytes: expression, activity and role, modulating factors and consequences for antiretroviral therapies.Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics.Transporter-mediated drug-drug interactions with oral antidiabetic drugs.Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.Double-transfected MDCK cells expressing human OCT1/MATE1 or OCT2/MATE1: determinants of uptake and transcellular translocation of organic cations.Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model.Intestinal drug transporter expression and the impact of grapefruit juice in humans.Effects of budesonide on P-glycoprotein expression in intestinal cell lines.Age-dependent redox status in the brain stem of NO-deficient hypertensive rats.Identification of budesonide and prednisone as substrates of the intestinal drug efflux pump P-glycoprotein.The influence of oral antidiabetic drugs on cellular drug uptake mediated by hepatic OATP family members.Berry anthocyanins and anthocyanidins exhibit distinct affinities for the efflux transporters BCRP and MDR1.Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination.Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes via in vivo and in vitro oxidation of midazolam and triazolam.Nitric oxide mediates increased P-glycoprotein activity in interferon-{gamma}-stimulated human intestinal cells.Machine learning-, rule- and pharmacophore-based classification on the inhibition of P-glycoprotein and NorA.P-glycoprotein and multidrug resistance-associated protein 2 are oppositely altered in brain of rats with thioacetamide-induced acute liver failure.High levels of P-glycoprotein activity in human lymphocytes in the first 6 months of life.Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables.Intestinal absorption of pallidifloside D are limited by P-glycoprotein in mice.Shedding light on drug transport: structure and function of the P-glycoprotein multidrug transporter (ABCB1).Effect of Phoneutria nigriventer venom on the expression of junctional protein and P-gp efflux pump function in the blood-brain barrier.P-glycoprotein (P-gp)-mediated efflux limits intestinal absorption of the Hsp90 inhibitor SNX-2112 in ratsEnhancing effect of Labrasol on the intestinal absorption of ganciclovir in ratsPharmacokinetics of the P-gp Inhibitor Tariquidar in Rats After Intravenous, Oral, and Intraperitoneal Administration
P2860
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P2860
Importance of P-glycoprotein for drug disposition in humans.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Importance of P-glycoprotein for drug disposition in humans.
@ast
Importance of P-glycoprotein for drug disposition in humans.
@en
type
label
Importance of P-glycoprotein for drug disposition in humans.
@ast
Importance of P-glycoprotein for drug disposition in humans.
@en
prefLabel
Importance of P-glycoprotein for drug disposition in humans.
@ast
Importance of P-glycoprotein for drug disposition in humans.
@en
P2860
P1476
Importance of P-glycoprotein for drug disposition in humans.
@en
P2093
P2860
P356
10.1046/J.1365-2362.33.S2.4.X
P478
33 Suppl 2
P577
2003-11-01T00:00:00Z