p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein.
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p53 regulation of G(2) checkpoint is retinoblastoma protein dependentPhosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damageFOXP3 up-regulates p21 expression by site-specific inhibition of histone deacetylase 2/histone deacetylase 4 association to the locusp53-dependent ceramide response to genotoxic stressp53-independent functions of the p19(ARF) tumor suppressorStructure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed fociThe cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene productsEffects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplicationIdentification of colorectal cancer patients with tumors carrying the TP53 mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy.Inhibition of papilloma progression by antisense oligonucleotides targeted to HPV11 E6/E7 RNA.Re-oxygenation improves hypoxia-induced pulp cell arrest.Binding of p300/CBP co-activators by polyoma large T antigen.The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway.Identification of positive and negative regulatory regions involved in regulating expression of the human cytomegalovirus UL94 late promoter: role of IE2-86 and cellular p53 in mediating negative regulatory function.Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesisp53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication.Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes.Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells.Induction of a retinoblastoma phosphatase activity by anticancer drugs accompanies p53-independent G1 arrest and apoptosis.Examination of the pRb-dependent and pRb-independent functions of E7 in vivo.E2F-Rb complexes assemble and inhibit cdc25A transcription in cervical carcinoma cells following repression of human papillomavirus oncogene expressionClinical and scientific impact of human papillomavirus on head and neck cancer.Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint.Mechanism-based screen establishes signalling framework for DNA damage-associated G1 checkpoint response.Human papillomavirus infections: epidemiology, pathogenesis, and therapy.Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.Biological activities and molecular targets of the human papillomavirus E7 oncoprotein.Overexpression of ANXA1 in penile carcinomas positive for high-risk HPVs.Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damageInhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein.p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E.HPV16-E7 expression causes fluorodeoxyuridine-mediated radiosensitization in SW620 human colon cancer cells.Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiationDifferential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy.Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivoHuman papillomaviruses: targeting differentiating epithelial cells for malignant transformation.Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.How the nucleolar sequestration of p53 protein or its interplayers contributes to its (re)-activation.
P2860
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P2860
p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein.
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
name
p53-dependent G1 arrest involv ...... illomavirus 16 E7 oncoprotein.
@ast
p53-dependent G1 arrest involv ...... illomavirus 16 E7 oncoprotein.
@en
type
label
p53-dependent G1 arrest involv ...... illomavirus 16 E7 oncoprotein.
@ast
p53-dependent G1 arrest involv ...... illomavirus 16 E7 oncoprotein.
@en
prefLabel
p53-dependent G1 arrest involv ...... illomavirus 16 E7 oncoprotein.
@ast
p53-dependent G1 arrest involv ...... illomavirus 16 E7 oncoprotein.
@en
P2093
P2860
P356
P1476
p53-dependent G1 arrest involv ...... illomavirus 16 E7 oncoprotein.
@en
P2093
B O Williams
B S Plunkett
M B Kastan
R J Slebos
T D Kessis
P2860
P304
P356
10.1073/PNAS.91.12.5320
P407
P577
1994-06-01T00:00:00Z