Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease.
about
Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9.The elusive role of the prion protein and the mechanism of toxicity in prion disease.Quantifying prion disease penetrance using large population control cohortsClinical Trial Research on Mongolian Medical Warm Acupuncture in Treating Insomnia.Genetic human prion disease modelled in PrP transgenic Drosophila.Losing sleep over mitochondria: a new player in the pathophysiology of fatal familial insomnia.Fatal Familial Insomnia: Clinical Aspects and Molecular Alterations.Misfolding leads the way to unraveling signaling pathways in the pathophysiology of prion diseases.Experimental Models of Inherited PrP Prion Diseases.Insights into Mechanisms of Transmission and Pathogenesis from Transgenic Mouse Models of Prion Diseases.Generation of a new infectious recombinant prion: a model to understand Gerstmann-Sträussler-Scheinker syndrome.Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice.Transgenic mice recapitulate the phenotypic heterogeneity of genetic prion diseases without developing prion infectivity: Role of intracellular PrP retention in neurotoxicityTowards authentic transgenic mouse models of heritable PrP prion diseases.Correction: Transgenic Fatal Familial Insomnia Mice Indicate Prion Infectivity-Independent Mechanisms of Pathogenesis and Phenotypic Expression of Disease.Experimental transfusion of variant CJD-infected blood reveals previously uncharacterised prion disorder in mice and macaque.Scientific Opinion on a request for a review of a scientific publication concerning the zoonotic potential of ovine scrapie prionsThe Role of the Mammalian Prion Protein in the Control of Sleep.Identification of new molecular alterations in fatal familial insomnia.Familial human prion diseases associated with prion protein mutations Y226X and G131V are transmissible to transgenic mice expressing human prion protein.Induction of a transmissible tau pathology by traumatic brain injury
P2860
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P2860
Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease.
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Transgenic fatal familial inso ...... notypic expression of disease.
@ast
Transgenic fatal familial inso ...... notypic expression of disease.
@en
type
label
Transgenic fatal familial inso ...... notypic expression of disease.
@ast
Transgenic fatal familial inso ...... notypic expression of disease.
@en
prefLabel
Transgenic fatal familial inso ...... notypic expression of disease.
@ast
Transgenic fatal familial inso ...... notypic expression of disease.
@en
P2093
P2860
P50
P1433
P1476
Transgenic fatal familial inso ...... notypic expression of disease.
@en
P2093
Alessandra Paladini
Cinzia Bisighini
Claudia Balducci
Edoardo Micotti
Fabio Fiordaliso
Francesca Baracchi
Galina V Beznoussenko
Gianluigi Forloni
Ihssane Bouybayoune
Ilaria Bertani
P2860
P304
P356
10.1371/JOURNAL.PPAT.1004796
P577
2015-04-16T00:00:00Z